ALDH Genetic Polymorphism
Khoom npe
HWM-GE015ALDH Genetic Polymorphism Detection Kit (ARMS -PCR)
Kab mob sib kis
ALDH2 noob (acetaldehyde dehydrogenase 2), nyob ntawm tib neeg chromosome 12. ALDH2 muaj esterase, dehydrogenase thiab reductase kev ua haujlwm tib lub sijhawm. Cov kev tshawb fawb tau pom tias ALDH2 yog ib qho enzyme metabolic ntawm nitroglycerin, uas hloov nitroglycerin rau hauv nitric oxide, yog li so cov hlab ntsha thiab txhim kho cov ntshav khiav. Txawm li cas los xij, muaj polymorphisms hauv ALDH2 gene, uas feem ntau yog nyob rau sab hnub tuaj Asia. Cov tsiaj qus ALDH2 * 1 / * 1 GG muaj zog metabolic muaj peev xwm, thaum hom heterozygous tsuas muaj 6% ntawm cov tsiaj qus-hom enzyme kev ua, thiab homozygous mutant hom yuav luag xoom enzyme kev ua, nrog metabolism tsis tshua muaj zog thiab tsis tuaj yeem ua tiav cov txiaj ntsig xav tau, yog li ua rau muaj kev phom sij rau tib neeg lub cev.
Channel
FAM | ALDH 2 |
ROX | Internal Control |
Technical Parameters
Cia | ≤-18 ℃ |
Txee lub neej | 12 hli |
Hom Qauv | EDTA anticoagulated ntshav |
CV | <5.0% |
LoD | 103Daim ntawv / ml |
Cov cuab yeej siv tau | Siv Biosystems 7500 Real-Time PCR System Siv Biosystems 7500 Fast Real-Time PCR Systems QuantStudio®5 Real-Time PCR Systems SLAN-96P Real-Time PCR Systems LightCycler®480 Real-Time PCR system LineGene 9600 Plus Real-Time PCR Detection System MA-6000 Real-Time Quantitative Thermal Cycler BioRad CFX96 Real-Time PCR System BioRad CFX Opus 96 Real-Time PCR System |
Ua hauj lwm Flow
Pom zoo extraction reagents: siv Blood Genome DNA Extraction Kit (DP318) los ntawm Tiangen Biotech (Beijing) Co., Ltd. los yog Blood Genome Extraction Kit (A1120) los ntawm Promega kom rho tawm EDTA anticoagulated ntshav Genomic DNA.
Pom zoo extraction reagents: Macro & Micro-Test General DNA/RNA Kit (HWTS-3019) (uas tuaj yeem siv nrog Macro & Micro-Test Automatic Nucleic Acid Extractor (HWTS-EQ011)) los ntawm Jiangsu Macro & Micro-Test Med-Tech Co., Ltd. Qhov pom zoo elution ntim yog100l miv.