Txij li thaum lub Tsib Hlis 2022, cov neeg mob mpox tau tshaj tawm hauv ntau lub tebchaws tsis muaj kab mob hauv ntiaj teb nrog kev sib kis hauv zej zog.
Lub Yim Hli 26, Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv Ntiaj Teb (WHO) tau tshaj tawm thoob ntiaj tebTswvyim npaj npaj thiab teb cov lus tebkom tsis txhob muaj kev sib kis ntawm tib neeg mus rau tib neeg kev sib kis ntawm mpox los ntawm kev sib koom tes thoob ntiaj teb, hauv cheeb tsam, thiab kev siv zog hauv tebchaws. Qhov no ua raws li kev tshaj tawm ntawm pej xeem kev noj qab haus huv xwm txheej ntawm kev txhawj xeeb thoob ntiaj teb los ntawm WHO Tus Thawj Coj-General ntawm 14 Lub Yim Hli.
Nws yuav tsum raug sau tseg tias mpox tshwm sim lub sijhawm no txawv ntawm qhov xyoo 2022, uas feem ntau kis tau ntawm cov txiv neej uas muaj kev sib deev nrog txiv neej, thiab cov neeg tuag ntawm cov neeg muaj mob tsawg dua 1%.
Cov kab mob tsis ntev los no "Clade Ib", uas yog qhov txawv ntawm Clade I, muaj kev tuag ntau dua. Qhov kev hloov tshiab no tau pib nthuav tawm hauv DRC lub Cuaj Hli dhau los, pib ntawm cov neeg ua haujlwm sib deev, thiab tam sim no tau kis mus rau lwm pab pawg, nrog rau cov menyuam yaus tshwj xeeb.
Africa CDC tau hais hauv tsab ntawv tshaj tawm lub hli tas los hais tias kev kis tus kabmob mpox tau pom hauv 10 lub tebchaws African xyoo no, suav nrog DRC, uas tau tshaj tawm 96.3% ntawm txhua tus neeg mob hauv tebchaws Africa xyoo no thiab 97% ntawm cov neeg tuag. Nws yog tsim nyog sau cia tias ze li ntawm 70% ntawm cov neeg mob hauv DRC yog cov menyuam yaus hnub nyoog qis dua 15 xyoo, thiab pab pawg no suav txog 85% ntawm cov neeg tuag hauv lub tebchaws.
Mpox yog ib tug zoonosis tshwm sim los ntawm tus kab mob mpox nrog lub sij hawm incubation ntawm 5 mus rau 21 hnub, feem ntau 6 mus rau 13 hnub. Tus neeg mob yuav muaj cov tsos mob xws li kub taub hau, mob taub hau thiab o ntawm cov qog nqaij hlav, tom qab ntawd los ntawm cov pob liab liab ntawm lub ntsej muag thiab lwm qhov ntawm lub cev, uas maj mam hloov mus ua pustules thiab kav ntev li ib lub lis piam ua ntej scabbing. Cov ntaub ntawv no kis tau los ntawm qhov pib ntawm cov tsos mob mus txog rau thaum cov pob khaus poob lawm.
Macro & Micro-Test yog muab cov kev ntsuam xyuas sai, cov khoom siv molecular thiab cov kev daws teeb meem rau kev kuaj pom tus kab mob mpox, pab kuaj tus kab mob mpox hauv lub sijhawm, saib xyuas nws keeb kwm, kab mob, kis tau tus mob thiab kev hloov pauv ntawm genomic:
Monkeypox Virus AntigenCov khoom siv kuaj pom (Immunochromatography)
Ib qho piv txwv yooj yim (piv txwv li pob khaus / caj pas) thiab tshwm sim sai hauv 10-15 min;
Siab rhiab heev nrog LoD ntawm 20pg / mL npog Clade I & II;
Qhov tshwj xeeb uas tsis muaj qhov cuam tshuam nrog tus kab mob me me, kab mob varicella zoster, tus kab mob rubella, tus kab mob herpes simplex, thiab lwm yam.
OPA ntawm 96.4% piv nrog NAATs;
Daim ntawv thov dav xws li kev lis kev cai, CDCs, khw muag tshuaj, chaw kho mob, tsev kho mob lossis hauv tsev.
Monkeypox-virus IgM/IgG Antibody Detection Kit(Immunochromatographhy)
Ib qho yooj yim ntsuas-dawb khiav lag luam thiab ceev tau tshwm sim nyob rau hauv 10 min;
Siab rhiab heev thiab tshwj xeeb npog Clade I & II;
Txheeb xyuas IgM thiab IgG los txiav txim siab mpox kab mob;
Daim ntawv thov dav xws li kev lis kev cai, CDCs, khw muag tshuaj, chaw kho mob, tsev kho mob lossis hauv tsev;
Tsim nyog rau kev tshuaj ntsuam loj ntawm kev xav tias tus kab mob mpox.
Monkeypox Virus Nucleic Acid Detection Kit (Enzymatic Probe Isothermal Amplification)
Siab rhiab heev nrog LoD ntawm 200 Daim Ntawv Luam / mL nrog IC, sib npaug rau florescence PCR;
Kev ua haujlwm yooj yim: Lysed qauv ntxiv rau lyophilized reagent raj rau qhov kev xav tau ncaj qha amplification enabled los ntawm ywj siab modules ntawm Easy Amp System;
Qhov tshwj xeeb tshaj plaws uas tsis muaj qhov sib txawv ntawm cov kab mob me me, tshuaj tiv thaiv kab mob, kab mob cowpox, kab mob mousepox, kab mob herpes simplex, varicella-zoster virus, thiab tib neeg genome, thiab lwm yam.;
Ib qho piv txwv yooj yim (cov kua dej tawm pob / oropharyngeal swab) thiab cov txiaj ntsig zoo tshaj plaws hauv 5 min;
Kev kho mob zoo heev npog Clade I & II nrog PPA ntawm 100%, NPA ntawm 100%, OPA ntawm 100% thiab Kappa Tus Nqi ntawm 1.000 piv nrog cov khoom siv Fluorescence PCR;
Lyophilized version tsuas yog xav tau kev thauj mus los hauv chav tsev kub thiab khaws cia ua rau muaj kev nkag tau yooj yim hauv txhua cheeb tsam;
Cov xwm txheej hloov tau yooj yim hauv cov chaw kho mob, chaw kho mob, ua ke nrog Ib qho yooj yim Amp rau kev tshawb nrhiav qhov xav tau;
Monkeypox Virus Nucleic Acid Detection Kit (Fluorescence PCR)
Dual gene tsom nrog siab rhiab heev nrog LoD ntawm 200 daim ntawv / mL;
Cov qauv yooj yim ntawm cov kua dej tawm pob, caj pas thiab cov ntshav;
Qhov tshwj xeeb tshaj plaws uas tsis muaj qhov sib txawv ntawm cov kab mob me me, tshuaj tiv thaiv kab mob, kab mob cowpox, kab mob mousepox, kab mob herpes simplex, varicella-zoster virus, thiab tib neeg genome, thiab lwm yam.;
Kev ua haujlwm yooj yim: ceev cov qauv lysis los ntawm cov qauv tso tawm reagent ntxiv rau cov tshuaj tiv thaiv raj;
Kev kuaj pom sai: tshwm sim hauv 40 min;
Qhov tseeb tau lees paub los ntawm kev tswj hwm sab hauv saib xyuas tag nrho cov txheej txheem tshawb pom;
Kev kho mob zoo heev npog Clade I & II nrog PPA ntawm 100%, NPA ntawm 99.40%, OPA ntawm 99.64% thiab Kappa Tus Nqi ntawm 0.9923 piv nrog sequencing;
Lyophilized version tsuas yog xav tau kev thauj mus los hauv chav tsev kub thiab khaws cia ua rau muaj kev nkag tau yooj yim hauv txhua cheeb tsam;
Tau tshaj nrog mainstream Fluorescence PCR Systems;
Cov xwm txheej yooj yim rau tsev kho mob, CDCs thiab chaw kuaj mob;
Orthopox Virus Universal Hom / Monkeypox Virus Nucleic Acid Detection Kit (Fluorescence PCR)
Tag nrho cov kev pab them nqi: kuaj tag nrho 4 tus kab mob orthopox uas tuaj yeem kis tau rau tib neeg thiab cov mpox uas muaj ntau (Clade I&II suav nrog) hauv ib qho kev sim kom tsis txhob raug kuaj pom;
Siab rhiab heev nrog LoD ntawm 200 daim ntawv / mL;
Qhov tshwj xeeb tshaj plaws uas tsis muaj kev sib cuam tshuam nrog lwm cov kab mob ua rau pob khaus xws li tus kab mob herpes simplex, varicella-zoster tus kab mob, thiab tib neeg genome, thiab lwm yam.;
Kev ua haujlwm yooj yim: ceev cov qauv lysis los ntawm cov qauv tso tawm reagent kom ntxiv rau hauv ib lub raj tshuaj tiv thaiv tsis zoo;
Kev kuaj pom sai: nrawm nrawm nrog qhov tshwm sim hauv 40 min;
Qhov tseeb tau lees paub los ntawm kev tswj hwm sab hauv saib xyuas tag nrho cov txheej txheem tshawb pom;
Tau tshaj nrog mainstream Fluorescence PCR Systems;
Cov xwm txheej yooj yim rau tsev kho mob, CDCs thiab chaw kuaj mob;
MonkeypoxVirus Typing uaNucleicAcidDkev xaivKnws (FLuorescence PCR)
Ib txhij txheeb xyuas Clade I thiab Clade II, uas yog qhov tseem ceeb rau kev nkag siab txog cov yam ntxwv ntawm tus kabmob kis, taug qab nws txoj kev sib kis, thiab tsim cov phiaj xwm tiv thaiv thiab tswj kev ntsuas.
Siab rhiab heev nrog LoD ntawm 200 daim ntawv / mL;
Cov qauv yooj yim ntawm cov kua dej tawm pob, oropharyngeal swab thiab serum;
Qhov tshwj xeeb tshwj xeeb yam tsis muaj qhov sib txawv ntawm Clade I thiab II, lwm yam kab mob ua rau pob khaus xws li tus kab mob herpes simplex, kab mob varicella-zoster, thiab tib neeg genome, thiab lwm yam.;
Kev ua haujlwm yooj yim: ceev cov qauv lysis los ntawm cov qauv tso tawm reagent kom ntxiv rau hauv ib lub raj tshuaj tiv thaiv tsis zoo;
Kev kuaj pom sai: tshwm sim hauv 40 min;
Qhov tseeb tau lees paub los ntawm kev tswj hwm sab hauv saib xyuas tag nrho cov txheej txheem tshawb pom;
Lyophilized version tsuas yog xav tau kev thauj mus los hauv chav tsev kub thiab khaws cia ua rau muaj kev nkag tau yooj yim hauv txhua cheeb tsam;
Tau tshaj nrog mainstream Fluorescence PCR Systems;
Cov xwm txheej yooj yim rau tsev kho mob, CDCs thiab chaw kuaj mob;
Monkey Virus Universal Whole GenomeKev kuaj pomKit (Multi-PCR NGS)
Tshiab tsim Monkeypox Virus Whole Genome Detection Kit los ntawm Macro & Micro-Test rau cov xwm txheej sib txawv, ua ke nrog ONT nanopore sequencer, tuaj yeem tau txais MPXV tag nrho cov genome ib ntus nrog kev pab them nqi tsawg dua 98% hauv 8 teev.
Yooj yim rau kev khiav lag luam: patented one-step amplification technology, tag nrho cov kab mob genome ntawm mpox tus kab mob tuaj yeem tau los ntawm ib puag ncig amplification;
rhiab heev thiab raug: kuaj pom cov qauv qis rau 32CT, thiab 600bp amplicon nanopore sequencing tuaj yeem ua tau raws li kev sib dhos genome zoo dua;
Ultra-ceev: ONT tuaj yeem ua tiav genome los ua ke hauv 6-8 teev;
Kev sib raug zoo dav: nrog ONT, Qi Carbon, SALUS Pro, lllumina, MGI thiab lwm yam 2ndthiab 3rdtiam sequencers.
Ultra-rhiab heevMonkey Virus Whole GenomeKev kuaj pomKit-Illumina/MGI(Multi-PCR NGS)
Hais txog ntau tus uas twb muaj lawm 2ndtiam neeg sequencers thoob ntiaj teb, Macro & Micro-Test kuj tau tsim cov khoom siv ultra-rhiab heev hloov mus rau lub ntsiab lus sib txuas kom ua tiav cov qauv qis qis ntawm cov kab mob genome sequencing;
Kev ua kom muaj txiaj ntsig zoo: 1448 khub ntawm 200bp amplicon ultra-dense primer tsim rau kev ua kom pom kev zoo siab thiab kev pab them nqi;
Kev ua haujlwm yooj yim: Mpox tus kab mob llumina / MGI lub tsev qiv ntawv tuaj yeem tau txais los ntawm ob-thooj amplification hauv 4 teev, zam kev tsim cov tsev qiv ntawv nyuaj thiab cov nqi reagent;
Siab rhiab heev: kuaj pom cov qauv qis rau 35CT, ua tau zoo kom tsis txhob muaj qhov tsis zoo tshwm sim los ntawm kev puas tsuaj los ntawm cov khoom tawg lossis cov ntawv luam tsawg;
Wide compatibility nrog mainstream 2ndtiam sequencers xws li lllumina, Salus Pro los yog MGI;Txog tam sim no, ntau dua 400 qhov chaw kho mob tau ua tiav.
Post lub sij hawm: Aug-28-2024