Txhua xyoo nyob rau lub Plaub Hlis 17th yog World Cancer Day.
01 World Cancer Incidence Overview
Nyob rau hauv xyoo tas los no, nrog kev nce ntxiv ntawm tib neeg lub neej thiab kev puas siab puas ntsws, qhov tshwm sim ntawm cov qog nqaij hlav kuj nce xyoo los ntawm xyoo.
Cov qog nqaij hlav qog nqaij hlav (mob qog noj ntshav) tau dhau los ua ib qho teeb meem loj rau pej xeem kev noj qab haus huv uas cuam tshuam rau kev noj qab haus huv ntawm cov pej xeem Suav.Raws li cov ntaub ntawv tshawb fawb zaum kawg, kev tuag ntawm cov qog nqaij hlav qog noj ntshav suav txog 23.91% ntawm tag nrho cov ua rau tuag ntawm cov neeg nyob hauv, thiab qhov tshwm sim thiab tuag ntawm cov qog nqaij hlav tau nce ntxiv hauv kaum xyoo dhau los.Tab sis mob qog noj ntshav tsis txhais hais tias "txoj lus tuag."Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv (World Health Organization) tau qhia meej tias ntev npaum li nws tau kuaj pom ntxov, 60%-90% ntawm cov qog nqaij hlav tuaj yeem kho tau!Ib feem peb ntawm cov qog nqaij hlav tuaj yeem tiv thaiv tau, ib feem peb ntawm cov qog nqaij hlav yog kho tau, thiab ib feem peb ntawm cov qog nqaij hlav tuaj yeem kho kom lub neej ntev.
02 Lub qog yog dab tsi
Tumor yog hais txog cov kab mob tshiab uas tsim los ntawm kev loj hlob ntawm cov ntaub so ntswg hauv zos nyob rau hauv kev ua ntawm ntau yam qog nqaij hlav.Cov kev tshawb fawb tau pom tias cov qog hlwb tau hloov pauv metabolic txawv ntawm cov cell qub.Nyob rau tib lub sijhawm, cov qog hlwb tuaj yeem hloov pauv mus rau qhov hloov pauv hauv qhov chaw metabolic los ntawm kev hloov ntawm glycolysis thiab oxidative phosphorylation.
03 Kev Kho Mob Kho Mob Rau Tus Kheej
Kev kho mob qog noj ntshav ntawm tus kheej yog ua raws li cov ntaub ntawv kuaj mob ntawm tus kab mob lub hom phiaj cov noob thiab cov txiaj ntsig ntawm cov pov thawj-raws li kev tshawb fawb kho mob.Nws muab lub hauv paus rau cov neeg mob kom tau txais cov phiaj xwm kho kom raug, uas tau dhau los ua tus qauv ntawm kev kho mob niaj hnub no.Cov kev tshawb fawb soj ntsuam tau lees paub tias los ntawm kev txheeb xyuas cov noob hloov pauv ntawm biomarkers, gene SNP typing, gene thiab nws cov protein qhia cov xwm txheej hauv cov qauv ntawm cov qog nqaij hlav rau cov neeg mob qog noj ntshav kom kwv yees cov tshuaj muaj txiaj ntsig thiab ntsuas kev ntsuas, thiab qhia kev kho mob rau tus kheej, nws tuaj yeem txhim kho kev ua tau zoo thiab txo qhov tsis zoo. cov tshuaj tiv thaiv, los txhawb kev siv cov khoom siv kho mob kom muaj nuj nqis.
Kev kuaj mob qog noj ntshav tuaj yeem muab faib ua 3 yam tseem ceeb: kev kuaj mob, kev kho mob, thiab kev kho mob.Kev kuaj mob yog nyob ntawm qhov tseem ceeb ntawm qhov hu ua "kev kho mob pathology" lossis cov tshuaj kho tus kheej, thiab ntau thiab ntau cov tshuaj tiv thaiv kab mob thiab cov tshuaj tiv thaiv me me uas tuaj yeem ua rau cov qog nqaij hlav tshwj xeeb cov noob caj noob ces thiab cov kev taw qhia tuaj yeem siv rau kev kho cov qog.
Molecular targeted therapy ntawm cov qog lub hom phiaj cov cim molecules ntawm cov qog hlwb thiab cuam tshuam rau hauv cov txheej txheem ntawm cov qog nqaij hlav cancer.Nws cov nyhuv yog feem ntau ntawm cov qog nqaij hlav, tab sis muaj kev cuam tshuam me ntsis rau cov hlwb qub.Cov qog loj hlob zoo receptors, teeb liab hloov pauv molecules, cell cycle proteins, apoptosis regulators, proteolytic enzymes, vascular endothelial kev loj hlob, thiab lwm yam tuaj yeem siv los ua cov hom phiaj molecular rau kev kho mob qog.Thaum Lub Kaum Ob Hlis 28, 2020, "Kev Tswj Xyuas Kev Ntsuas rau Kev Siv Tshuaj Siv Tshuaj Antineoplastic (Siv)" tshaj tawm los ntawm National Health thiab Medical Commission tau taw qhia meej tias: Rau cov tshuaj uas muaj cov hom phiaj meej, cov hauv paus ntsiab lus ntawm kev siv lawv yuav tsum ua raws li tom qab. lub hom phiaj kuaj gene.
04 Tumor-targeted genetic testing
Muaj ntau hom kev hloov caj ces hauv cov qog, thiab ntau hom kev hloov caj ces siv cov tshuaj sib txawv.Tsuas yog los ntawm kev qhia meej txog hom kev hloov pauv ntawm cov noob thiab xaiv txoj kev siv tshuaj kho mob kom raug cov neeg mob tau txais txiaj ntsig.Txoj kev tshawb nrhiav molecular tau siv los txheeb xyuas qhov hloov pauv ntawm cov noob muaj feem cuam tshuam nrog cov tshuaj nquag hauv cov qog.Los ntawm kev txheeb xyuas qhov cuam tshuam ntawm cov noob caj noob ces ntawm kev ua tau zoo ntawm cov tshuaj, peb tuaj yeem pab cov kws kho mob tsim cov phiaj xwm kho mob uas tsim nyog tshaj plaws
05 Kev daws teeb meem
Macro & Micro-Test tau tsim cov khoom siv tshawb nrhiav rau cov qog noob caj noob ces, muab kev daws teeb meem tag nrho rau kev kho mob qog noj ntshav.
Tib neeg EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR)
Cov khoom siv no yog siv rau hauv vitro qualitatively nrhiav tau ntawm kev hloov pauv hauv exons 18-21 ntawm EGFR noob hauv cov qauv los ntawm tib neeg cov neeg mob qog noj ntshav tsis me me.
1. Lub kaw lus qhia txog kev tswj xyuas kev siv sab hauv, uas tuaj yeem saib xyuas cov txheej txheem kev sim thiab xyuas kom zoo ntawm qhov kev sim.
2. Siab rhiab heev: Kev kuaj pom ntawm nucleic acid cov tshuaj tiv thaiv tuaj yeem kuaj pom qhov hloov pauv ntawm 1% nyob rau hauv keeb kwm yav dhau ntawm 3ng / μL hom tsiaj qus.
3. Qhov tshwj xeeb siab: Tsis muaj qhov cuam tshuam nrog cov tsiaj qus tib neeg genomic DNA thiab lwm hom mutant.
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KRAS 8 Mutations Detection Kit (Fluorescence PCR)
Cov khoom siv no yog npaj rau hauv vitro zoo nrhiav pom ntawm 8 kev hloov pauv hauv codons 12 thiab 13 ntawm K-ras gene hauv cov DNA rho tawm los ntawm tib neeg paraffin-embedded pathological seem.
1. Lub kaw lus qhia txog kev tswj xyuas kev siv sab hauv, uas tuaj yeem saib xyuas cov txheej txheem kev sim thiab xyuas kom zoo ntawm qhov kev sim.
2. Siab rhiab heev: Kev kuaj pom ntawm nucleic acid cov tshuaj tiv thaiv tuaj yeem kuaj pom qhov hloov pauv ntawm 1% nyob rau hauv keeb kwm yav dhau ntawm 3ng / μL hom tsiaj qus.
3. Qhov tshwj xeeb siab: Tsis muaj qhov cuam tshuam nrog cov tsiaj qus tib neeg genomic DNA thiab lwm hom mutant.
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Human EML4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Cov khoom siv no yog siv los soj ntsuam 12 yam kev hloov pauv ntawm EML4-ALK fusion noob hauv cov qauv ntawm tib neeg cov qog nqaij hlav qog noj ntshav hauv vitro.
1. Lub kaw lus qhia txog kev tswj xyuas kev siv sab hauv, uas tuaj yeem saib xyuas cov txheej txheem kev sim thiab xyuas kom zoo ntawm qhov kev sim.
2. High rhiab heev: Cov khoom siv no tuaj yeem ntes cov kev hloov pauv ntawm fusion tsawg li 20 daim ntawv.
3. Qhov tshwj xeeb siab: Tsis muaj qhov cuam tshuam nrog cov tsiaj qus tib neeg genomic DNA thiab lwm hom mutant.
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Human ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Cov khoom siv no yog siv rau hauv vitro zoo nrhiav pom ntawm 14 hom ROS1 fusion gene mutations hauv tib neeg cov qog nqaij hlav qog nqaij hlav me me.
1. Lub kaw lus qhia txog kev tswj xyuas kev siv sab hauv, uas tuaj yeem saib xyuas cov txheej txheem kev sim thiab xyuas kom zoo ntawm qhov kev sim.
2. High rhiab heev: Cov khoom siv no tuaj yeem ntes cov kev hloov pauv ntawm fusion tsawg li 20 daim ntawv.
3. Qhov tshwj xeeb siab: Tsis muaj qhov cuam tshuam nrog cov tsiaj qus tib neeg genomic DNA thiab lwm hom mutant.
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Tib neeg BRAF Gene V600E Mutation Detection Kit (Fluorescence PCR)
Cov khoom siv kuaj no yog siv los ntsuas qhov zoo ntawm BRAF gene V600E kev hloov pauv hauv paraffin-embedded cov ntaub so ntswg ntawm tib neeg melanoma, mob qog noj ntshav, qog nqaij hlav qog noj ntshav thiab mob ntsws cancer hauv vitro.
1. Lub kaw lus qhia txog kev tswj xyuas kev siv sab hauv, uas tuaj yeem saib xyuas cov txheej txheem kev sim thiab xyuas kom zoo ntawm qhov kev sim.
2. Siab rhiab heev: Kev kuaj pom ntawm nucleic acid cov tshuaj tiv thaiv tuaj yeem kuaj pom qhov hloov pauv ntawm 1% nyob rau hauv keeb kwm yav dhau ntawm 3ng / μL hom tsiaj qus.
3. Qhov tshwj xeeb siab: Tsis muaj qhov cuam tshuam nrog cov tsiaj qus tib neeg genomic DNA thiab lwm hom mutant.
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| Catalog Number | Khoom npe | Specification |
| HWTS-TM012A/B | Tib neeg EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR) | 16 xeem/kit, 32 xeem/kit |
| HWTS-TM014A/B | KRAS 8 Mutations Detection Kit (Fluorescence PCR) | 24 xeem/kit, 48 xeem/kit |
| HWTS-TM006A/B | Human EML4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 20 xeem/kit, 50 xeem/kit |
| HWTS-TM009A/B | Human ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 20 xeem/kit, 50 xeem/kit |
| HWTS-TM007A/B | Tib neeg BRAF Gene V600E Mutation Detection Kit (Fluorescence PCR) | 24 xeem/kit, 48 xeem/kit |
| HWM-GE010A | Tib neeg BCR-ABL Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 24 xeem/kit |
Post lub sij hawm: Apr-17-2023