Fully-Automated Sample-rau-Answer C. Sib Nqus Kab Mob Sib Nqus

Dab tsi ua rau tus kab mob C. Diff?

C.Diff kab mob yog tshwm sim los ntawm ib tug kab mob hu uaClostridioides difficile (C. difficile), uas feem ntau nyob tsis zoo nyob rau hauv txoj hnyuv. Txawm li cas los xij, thaum lub plab cov kab mob sib npaug raug cuam tshuam, feem ntau siv tshuaj tua kab mob dav dav, C. difficile tuaj yeem loj hlob ntau dhau thiab tsim cov co toxins, ua rau muaj kab mob.

Cov kab mob no muaj nyob hauv ob qho tib sitshuaj lomthiab cov ntaub ntawv uas tsis yog-toxigenic, tab sis tsuas yog cov kab mob toxigenic (toxins A thiab B) ua rau kab mob. Lawv ua rau mob los ntawm kev cuam tshuam cov plab hnyuv epithelial hlwb. Toxin A feem ntau yog ib qho enterotoxin uas ua rau lub plab hauv ob sab phlu, nce permeability, thiab nyiam lub cev tiv thaiv kab mob uas tso tawm cov kab mob cytokines. Toxin B, lub zog ntau dua cytotoxin, tsom rau cov actin cytoskeleton ntawm cov hlwb, ua rau lub xov tooj ntawm tes sib npaug, detachment, thiab kawg ntawm tes tuag. Ua ke, cov co toxins no ua rau cov ntaub so ntswg puas thiab muaj zog tiv thaiv kab mob, uas tshwm sim raws li colitis, raws plab, thiab nyob rau hauv mob hnyav, pseudomembranous colitis - ib qho mob loj ntawm txoj hnyuv.

Ua li casC. Qhov txawvkis mus?

C.Diff kis tau yooj yim heev. Nws muaj nyob hauv tsev kho mob, feem ntau pom hauv ICUs, ntawm tes ntawm cov neeg ua haujlwm hauv tsev kho mob, hauv tsev kho mob hauv pem teb thiab tes tuav, ntawm cov ntsuas hluav taws xob, thiab lwm yam khoom siv kho mob ...

Yam Tseem Ceeb rau C. Kab Mob Kab Mob

• ●Kev mus pw hauv tsev kho mob ntev;

• ●Kev kho mob antimicrobial;

• ●Cov tshuaj tua kab mob;

• ●Kev phais tsis ntev los no (lub tsho plab, plab hnyuv, phais plab);

• ●Naso-gastric khoom noj khoom haus;

• ●Ua ntej C. kab mob sib txawv;

Cov tsos mob ntawm C. Diff kab mob

C. diff kab mob tuaj yeem ua rau tsis xis nyob heev. Cov neeg feem coob muaj raws plab tsis tu ncua thiab tsis xis nyob hauv plab. Cov tsos mob feem ntau yog: raws plab, mob plab, xeev siab, tsis qab los noj mov, ua npaws.

Raws li C. diff kab mob hnyav dua, yuav muaj kev txhim kho ntawm daim ntawv nyuaj ntawm C. diff hu ua colitis, pseudomembranous enteritis thiab txawm tuag.

Kev kuaj mobntawm C. Diff Infection

Kab mob kab mob:rhiab heev tab sis siv sij hawm (2-5 hnub), tsis tuaj yeem paub qhov txawv ntawm cov kab mob toxigenic thiab non-toxigenic;

Toxin Culture:txheeb xyuas cov kab mob toxigenic uas ua rau muaj kab mob tab sis siv sijhawm ntev (3-5 hnub) thiab tsis tshua nkag siab;

Kev kuaj pom GDH:ceev (1-2 teev) thiab tus nqi-zoo, rhiab heev tab sis tsis tuaj yeem paub qhov txawv ntawm toxigenic thiab non-toxigenic hom;

Cell Cytotoxicity Neutralization Assay (CCNA): kuaj pom cov tshuaj lom A thiab B nrog lub siab rhiab heev tab sis siv sijhawm (2-3 hnub), thiab xav tau cov chaw tshwj xeeb thiab cov neeg ua haujlwm cob qhia;

Toxin A/B ELISA: Kev sim yooj yim thiab nrawm (1-2 teev) nrog qis rhiab heev thiab tsis tshua muaj qhov tsis zoo;

Nucleic Acid Amplification Tests (NAATs): Ceev ceev (1-3hrs) thiab rhiab heev & tshwj xeeb, kuaj cov noob lub luag haujlwm rau kev tsim cov tshuaj lom;

Tsis tas li ntawd, kev ntsuam xyuas cov duab los kuaj cov hnyuv, xws li CT scans thiab X-rays, kuj tseem siv tau los pab rau kev kuaj mob C. diff thiab cov teeb meem ntawm C. diff, xws li colitis.

Kev kho mob C. Diff kab mob

Muaj ntau txoj kev kho mob muaj rauC. txawv kab mob. Hauv qab no yog cov kev xaiv zoo tshaj plaws:

• ●Cov tshuaj tua kab mob hauv qhov ncauj zoo li vancomycin, metronidazole lossis fidaxomicin feem ntau yog siv raws li cov tshuaj tuaj yeem dhau los ntawm lub plab zom mov thiab mus txog rau txoj hnyuv uas C. diff bacteria nyob.

• ●Intravenous metronidazole tuaj yeem siv rau kev kho mob yog tias tus kab mob C. diff mob hnyav heev.

• ●Kev hloov pauv Fecal microbiota tau pom tias muaj txiaj ntsig zoo hauv kev kho mob C. qhov sib txawv thiab cov kab mob loj C. diff uas tsis teb rau cov tshuaj tua kab mob.

• ●Kev phais yuav tsim nyog rau cov mob hnyav.

Diagnostic solution los ntawm MMT

Nyob rau hauv kev teb rau qhov xav tau kom ceev, raug kuaj xyuas C. difficile, peb qhia peb cov khoom siv tshiab Nucleic Acid Detection Kit rau Clostridium difficile toxin A/B noob, txhawb cov kws kho mob kom kuaj xyuas ntxov thiab raug thiab txhawb kev sib ntaus tawm tsam hauv tsev kho mob kis kab mob.

图片链接:

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  ●Siab rhiab heev: Pom tsawg li200 CFU/ml,;

• 
  
  ●Qhov tseeb Target: Qhia meej meej C. difficile toxin A/B noob, txo qis qhov tsis zoo;

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  ●Direct Pathogen Detection: Siv cov tshuaj nucleic acid txhawm rau txheeb xyuas cov tshuaj lom neeg, tsim kom muaj tus qauv kub rau kev kuaj mob.

• 
  
  ●Siab tshaj nrogPCR cov cuab yeej tseem ceeb hais txog ntau qhov chaw sim;

Qauv-rau-lus tebKev daws teeb meem ntawm Macro & Micro-Test's AIO800 Mobile PCR Lab

 

• ●Sample-rau-Teb Automation - Load thawj cov raj xa dej (1.5-12 mL) ncaj qha, tshem tawm cov kev tuav pov hwm. Extraction, amplification, thiab nrhiav kom tau tag nrho automated, txo tes-rau lub sij hawm thiab tib neeg yuam kev.

• ●Yim-Layer Contamination Protection - Kev taw qhia ntawm huab cua, tsis zoo siab, HEPA pom, UV sterilization, kaw cov tshuaj tiv thaiv, thiab lwm yam kev tiv thaiv kev sib koom ua ke tiv thaiv cov neeg ua haujlwm thiab xyuas kom ntseeg tau cov txiaj ntsig zoo thaum lub sij hawm ntsuas kev ntsuas siab.

Yog xav paub ntxiv:

Tsab ntawv xov xwm no tshwm sim thawj zaug https://www.mmtest.com/nucleic-acid-detection-kit-for-clostridium-difficile-toxin-ab-gene-fluorescence-pcr-product/

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