Kab mob fungal, qhov tseem ceeb ntawm vaginitis thiab mob ntsws fungal - Candida Albicans

Qhov tseem ceeb ntawm Kev Tshawb Fawb

Cov kab mob fungal candidiasis (tseem hu ua candidal kab mob) yog qhov tshwm sim. Muaj ntau hom Candida thiabNtau tshaj 200 hom Candida ua taunrhiav tau tam sim no.Candida albicans (CA) yog cov kab mob feem ntau, uas account rau li ntawm 70% ntawm tag nrho cov kev kuaj mob.CA, tseem hu ua Candida dawb, feem ntau parasitizes ntawm cov mucous daim nyias nyias ntawm tib neeg daim tawv nqaij, lub qhov ncauj kab noj hniav, plab hnyuv kab mob, qhov chaw mos, thiab lwm yam. Thaum tib neeg lub cev tiv thaiv kab mob yog txawv txav los yog lub cev flora tsis tshuav, C.A muaj ua rau cov kab mob hauv lub cev, kab mob hauv qhov chaw mos, kab mob ua pa qis, thiab lwm yam.

Vaginitis:Kwv yees li 75% ntawm cov poj niam muaj vulvovaginal candidiasis (VVC) tsawg kawg ib zaug hauv lawv lub neej, thiab ib nrab ntawm lawv yuav rov zoo dua. Ntxiv nrog rau cov tsos mob ntawm lub cev mob xws li vulvovaginal khaus thiab kub hnyiab, mob hnyav tuaj yeem ua rau tsis xis nyob, uas yog pom tseeb dua thaum hmo ntuj, thiab nws tseem cuam tshuam rau tus neeg mob lub siab thiab lub siab lub ntsws. VVC tsis muaj cov tsos mob tshwj xeeb, thiab kev kuaj sim yog tus yuam sij rau kev kuaj mob.

Pulmonary fungal kab mob:CA kev kis kab mob yog ib qho tseem ceeb ntawm kev tuag los ntawm kev mob hauv tsev kho mob thiab nws suav txog li 40% among cov neeg mob hnyav hauv ICU. Ib qho kev ntsuam xyuas rov qab los ntawm ntau qhov chaw ntawm cov kab mob pulmonary fungal hauv Suav teb los ntawm 1998 txog 2007 pom tias pulmonary candidiasis suav txog 34.2%, ntawm cov uas.CA suav txog 65% ntawm pulmonary candidiasis. Ua pa CA Kev kis kab mob tsis muaj cov tsos mob tshwm sim thiab muaj qhov tshwj xeeb tsawg hauv cov duab pom, ua rau kev kuaj mob ntxov nyuaj. Cov kws tshaj lij pom zoo rau kev kuaj mob thiab kev kho mob ntawm cov kab mob pulmonary fungal pom zoo kom siv cov hnoos qeev uas tsim nyog tau hnoos heev, ntxiv dag zog rau kev sim tshuaj molecular lom, thiab muab cov phiaj xwm kho cov kab mob fungal.

Hom qauv

 

Kev Tshuaj Ntsuam Xyuas

Khoom nta

Kev ua tau zoo:Isothermal amplification rau yooj yim amplification nrog cov txiaj ntsig hauv 30 min;

High specification: Specific primer thiab sojntsuam (rProbe)tsimrau thaj tsam uas tau txais kev cawmdim heev ntawm CAnrog lub kaw lus kaw tag nrho txhawm rau txheeb xyuas CA DNA hauv cov qauv.Tsis muaj kev cuam tshuam nrog lwm cov kab mob urogenital kab mob;

Siab rhiab heev: LoD ntawm 10² kab mob / ml;

QC siv tau: Exogenous sab hauv siv los tswj reagent thiab kev ua haujlwm zoo thiab tsis txhob muaj qhov tsis zoo;

Cov txiaj ntsig raug: 1,000 tus neeg mob ntau-center soj ntsuam kev soj ntsuam nrog atag nrho tus nqi ua rawsof 99.7%;

Kev pabcuam dav dav ntawm serotypes: Txhua serotypes ntawm Candida albicans A, B, Cnpog nrogcov txiaj ntsig zoo ib yampiv nrognrhiav kom tau ib ntus;

Qhib reagents: Tau tshaj PCR tam sim nosystua ems.

Cov ntaub ntawv khoom

Khoom Code	Khoom npe	Specification	Daim ntawv pov thawj No.
HWM-FG005	Nucleic Acid Detection Kit raws li Enzymatic Probe Isothermal Amplification (EPIA) rau Candida Albicans	50 test/kit
HWM-EQ008	Yooj yim AmpReal-time Fluorescence Isothermal Detection System	HWM-1600P 4 fluorescence channels	NMPA2023322059 ib
HWM-EQ009		HWM-1600s 2fluorescence channels