Kev tshuaj xyuas ntawmDaim Ntawv Tshawb Fawb Qub
Kab mob Respiratory Syncytial Virus (RSV) thiab Human Metapneumovirus (HMPV) yog cov kab mob uas ua rau mob ntsws.ob qho tib si pathogens cuam tshuam nrog hauvKab mob Pneumoviridaetsev neeguas feem ntau tsis meej pem hauv cov menyuam yaus uas muaj kab mob ua pa nyuaj. Txawm hais tias lawv cov kev nthuav qhia hauv kev kho mob sib tshooj, cov ntaub ntawv saib xyuas yav tom ntej (2016–2020) los ntawm 7 lub tsev kho mob menyuam yaus hauv Tebchaws Meskas - uas muaj 8,605 tus neeg mob - qhia txog qhov sib txawv tseem ceeb hauv lawv cov pej xeem uas muaj kev pheej hmoo siab, qhov hnyav ntawm tus kab mob, thiab kev tswj hwm kev kho mob. Kev tshawb fawb no siv kev tsim qauv nquag, yav tom ntej nrog kev sau thiab kuaj cov nasopharyngeal swab rau 8 tus kab mob ua pa, muab thawj qhov kev sib piv loj, lub ntiaj teb tiag tiag rau cov kws kho mob menyuam yaus. Los ntawm kev tshuaj xyuas cov nqi pw hauv tsev kho mob, kev nkag mus rau ICU, kev siv lub tshuab ua pa, thiab kev nyob hauv tsev kho mob ntev (≥3 hnub), nws tsim kom muaj lub hauv paus tseem ceeb ua ntej kev cuam tshuam epidemiological rau lub sijhawm ntawm kev txhaj tshuaj tiv thaiv RSV tshiab (piv txwv li, cov tshuaj tiv thaiv niam, cov tshuaj monoclonal ua haujlwm ntev) thiab tsim lub moj khaum rau kev tsim tshuaj tiv thaiv HMPV yav tom ntej.
Qhov Tseem Ceeb Tshawb Pom 1: Cov Ntaub Ntawv Sib Txawv Uas Muaj Kev Pheej Hmoo Siab
-RSV feem ntau cuam tshuam rau cov menyuam mos:Lub hnub nyoog nruab nrab ntawm kev pw hauv tsev kho mob tsuas yog 7 lub hlis xwb, nrog rau 29.2% ntawm cov neeg mob uas tau txais kev kho mob yog cov menyuam mos (0-2 lub hlis). RSV yog ib qho ua rau cov menyuam mos hnub nyoog qis dua 6 lub hlis raug pw hauv tsev kho mob, qhov hnyav ntawm tus kab mob no sib piv nrog hnub nyoog.
-HMPV tsom rau cov menyuam yaus loj dua thiab cov neeg uas muaj mob ua ke:Lub hnub nyoog nruab nrab ntawm kev pw hauv tsev kho mob yog 16 lub hlis, nrog rau qhov cuam tshuam ntau dua rau cov menyuam yaus hnub nyoog tshaj 1 xyoos. Qhov tseem ceeb, qhov tshwm sim ntawm cov mob nkeeg (piv txwv li, mob plawv, mob hlwb, mob ua pa) yog ntau dua ob npaug ntawm cov neeg mob HMPV (26%) piv rau cov neeg mob RSV (11%), qhia txog lawv qhov kev phom sij ntau dua.
Daim Duab 1. Kev faib tawm hnub nyoog ntawm kev mus ntsib ED thiab kev pw hauv tsev kho mobcuam tshuam nrog RSV lossis HMPV
rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Qhov Tseem Ceeb Tshawb Pom 2: Kev Sib Txawv ntawm Cov Lus Qhia Txog Kev Kho Mob
-RSV tshwm sim nrog cov tsos mob tseem ceeb ntawm kev ua pa hauv qab:Nws muaj feem cuam tshuam nrog mob ntsws bronchiolitis (76.7% ntawm cov neeg mob hauv tsev kho mob). Cov cim qhia tseem ceeb suav nrogkev rub ntawm phab ntsa hauv siab (76.9% cov neeg mob pw hauv tsev kho mob; 27.5% ED)thiabua pa ceev (91.8% cov neeg mob pw hauv tsev kho mob; 69.8% ED), ob qho tib si ntau dua li hauv HMPV.
-HMPV muaj feem yuav kub taub hau thiab mob ntsws ntau dua:Tau kuaj pom tias muaj mob ntsws (pneumonia) hauv 35.6% ntawm cov neeg mob HMPV uas tau pw hauv tsev kho mob—ob npaug ntawm tus nqi ntawm RSV.Kub taub hau yog ib qho tseem ceeb dua (83.6% cov neeg mob pw hauv tsev kho mob; 81% ED)Txawm hais tias cov tsos mob ntawm kev ua pa xws li ua pa nrov nrov thiab ua pa ceev ceev, feem ntau lawv tsis hnyav npaum li RSV.
Daim Duab 2.Cov yam ntxwv sib piv thiab kev kho mobchav kawmntawm RSV piv rau HMPV rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Kev Txheeb Xyuas: RSVfeem ntau ua rau muaj mob hnyav rau cov menyuam mos, uas ua rau muaj kev ua pa nyuaj heev (ua pa nrov nrov, rub rov qab) thiab mob bronchiolitis.HMPVfeem ntau cuam tshuam rau cov menyuam yaus loj dua uas muaj cov kab mob ua ke, muaj kub taub hau heev, muaj feem yuav mob ntsws ntau dua, thiab feem ntau ua rau muaj kev o ntawm lub cev dav dua.
Qhov Tseem Ceeb 3: Cov Qauv Caij Nyoog Tseem Ceeb
-RSV muaj qhov mob siab tshaj plaws thaum ntxov thiab kwv yees tau:Nws cov dej num muaj zog heev, feem ntau yog nce siab ntawmKaum Ib Hlis thiab Lub Ib Hlis, ua rau nws yog thawj qhov kev hem thawj rau cov menyuam mos thaum lub caij nplooj zeeg thiab lub caij ntuj no.
-HMPV nce siab dua tom qab nrog kev hloov pauv ntau dua:Nws lub caij tuaj txog lig dua, feem ntau yog thaum lub caij siab tshaj plawsLub Peb Hlis thiab Lub Plaub Hlis, thiab qhia tau tias muaj kev hloov pauv ntau xyoo thiab thaj chaw, feem ntau tshwm sim ua "nthwv dej thib ob" tom qab RSV poob qis.
Daim Duab 3.Kev kuaj mob PCR zoo rau txhua qhov chaw thiab txhua qhov chawetus nqi ntawm RSV thiab HMPV ntawm cov menyuam yaus hnub nyoog qis dua 18 xyoo uas muaj kev mus ntsib ED thiab kev pw hauv tsev kho mob cuam tshuam nrog kev kis tus kab mob ua pa hnyav (ARI).
Kev Tiv Thaiv thiab Kev Saib Xyuas: Ib Txoj Kev Npaj Ua Haujlwm Raws Li Pov Thawj
-Kev Tiv Thaiv RSV:Cov tswv yim tiv thaiv kab mob tam sim no muaj. Xyoo 2023, US FDA tau pom zoo rau cov tshuaj monoclonal antibody uas ua haujlwm ntev (Nirsevimab), uas tuaj yeem tiv thaiv cov menyuam mos rau lawv thawj 5 lub hlis. Tsis tas li ntawd, kev txhaj tshuaj tiv thaiv RSV ntawm niam ua rau muaj kev hloov pauv cov tshuaj tiv thaiv kab mob rau cov menyuam mos.
-Kev Tiv Thaiv HMPV:Tam sim no tsis muaj tshuaj tiv thaiv kab mob uas tau pom zoo. Txawm li cas los xij, muaj ntau yam tshuaj tiv thaiv kab mob (piv txwv li, AstraZeneca's RSV/HMPV ua ke) tab tom sim tshuaj. Cov niam txiv raug qhia kom paub txog cov xov xwm tshiab los ntawm cov tub ceev xwm saib xyuas kev noj qab haus huv pej xeem.
Nrhiav Kev Kho Mob Tam Sim No rau IB QHO ntawm cov "Chij Liab" no:
-Kub taub hau rau cov menyuam mos:Kub taub hau ≥38°C (100.4°F) rau txhua tus menyuam mos hnub nyoog qis dua 3 lub hlis.
-Kev Ua Pa Nce Siab:Ua pa ntau tshaj 60 zaus ib feeb rau cov menyuam mos hnub nyoog 1-5 lub hlis, lossis 40 zaus ib feeb rau cov menyuam yaus hnub nyoog 1-5 xyoos, qhia tias ua pa nyuaj.
-Cov Pa Pa Tsawg:Cov pa oxygen saturation (SpO₂) poob qis dua 90%, uas yog ib qho cim qhia txog kev mob hnyav uas pom muaj nyob rau hauv 30% ntawm RSV thiab 32.1% ntawm cov neeg mob HMPV hauv kev tshawb fawb no.
-Kev qaug zog lossis kev nyuaj siab ntawm kev noj mov:Muaj qhov tsis muaj zog lossis txo qis kev haus mis ntau dua ib feem peb hauv 24 teev, uas tuaj yeem ua rau lub cev qhuav dej.
Txawm hais tias muaj qhov sib txawv hauv kev kis kab mob thiab kev nthuav qhia hauv kev kho mob, kev sib txawv ntawm RSV thiab HMPV ntawm qhov chaw kho mob tseem nyuaj. Ntxiv mus, qhov kev hem thawj hauv kev kho mob nthuav dav dhau ob hom kab mob no, nrog rau cov kab mob xws li mob khaub thuas A thiab ntau yam kab mob sib kis thiab cov kab mob bacterial uas ua rau pej xeem muaj kev noj qab haus huv. Yog li ntawd, kev kuaj mob raws sijhawm thiab meej yog qhov tseem ceeb rau kev tswj hwm kev txhawb nqa, kev cais tawm zoo, thiab kev faib cov peev txheej kom raug.
Taw qhia txog AIO800 + 14-Pathogen Combined Detection Kit (Fluorescence PCR)(NMPA, CE, FDA, SFDA pom zoo)
Yuav kom ua tau raws li qhov kev thov no,Eudemon™ AIO800 Lub Tshuab Tshawb Nrhiav Nucleic Acid Tsis Siv Neeg Tag Nrho, ua ke nrog ib qho14-kab mob ua pa, muab kev daws teeb meem hloov pauv - xa cov lus tseeb"Qauv nkag, teb tawm"kuaj mob hauv 30 feeb xwb.
Qhov kev kuaj mob ua pa no ua rau pom tseebob qho tib si kab mob thiab kab mob bacterialos ntawm ib qho qauv, ua rau cov kws kho mob pem hauv ntej tuaj yeem txiav txim siab kho mob kom ntseeg siab, raws sijhawm, thiab tsom mus rau.
Cov yam ntxwv tseem ceeb ntawm lub kaw lus uas tseem ceeb rau koj cov neeg siv khoom
Kev Ua Haujlwm Tsis Siv Neeg Tag Nrho
Siv sijhawm tsawg dua 5 feeb los ua haujlwm. Tsis tas yuav muaj cov neeg ua haujlwm txawj ntse.
- Cov Txiaj Ntsig Sai
Lub sijhawm tig rov qab 30 feeb txhawb nqa cov chaw kho mob ceev.
- 14Kev Tshawb Nrhiav Kab Mob Ntau Yam
Kev txheeb xyuas tib lub sijhawm ntawm:
Cov kab mob:COVID-19, Influenza A & B, RSV, Adv, hMPV, Rhv, Parainfluenza types I-IV, HBoV, EV, CoV
Cov kab mob:MP,Cpn, SP
-Cov Tshuaj Reagents Lyophilized Ruaj Khoov ntawm Chav Kub (2–30 ° C)
Ua kom yooj yim rau kev khaws cia thiab kev thauj mus los, tshem tawm kev vam khom rau cov khoom siv txias.
Lub Tshuab Tiv Thaiv Kev Ua Phem Muaj Zog
11-txheej kev tiv thaiv kev ua qias tuaj suav nrog UV sterilization, HEPA filtration, thiab closed-cartridge workflow, thiab lwm yam.
Kev txheeb xyuas cov kab mob sai thiab dav dav yog lub hauv paus rau kev tswj hwm niaj hnub no ntawm cov menyuam yaus uas muaj kab mob ua pa. Lub kaw lus AIO800, nrog nws lub vaj huam sib luag multiplex PCR uas ua haujlwm tau 30 feeb, muab kev daws teeb meem zoo rau cov chaw ua haujlwm pem hauv ntej. Los ntawm kev ua kom pom tseeb ntawm RSV, HMPV, thiab lwm yam kab mob tseem ceeb thaum ntxov thiab raug, nws ua rau cov kws kho mob muaj peev xwm txiav txim siab kho mob, ua kom zoo dua kev siv tshuaj tua kab mob, thiab siv kev tswj kab mob zoo - thaum kawg txhim kho kev saib xyuas tus neeg mob thiab kev kho mob zoo.
#RSV #HMPV #Sai sai #Kev Txheeb Xyuas #Ua pa #Kab mob #Qauv-rau-Teb#Kev Ntsuas MacroMicro
Lub sijhawm tshaj tawm: Lub Kaum Ob Hlis-02-2025