Dab tsi yog dsibua npawsthiab DENVvirus?
Tus mob dengue fever yog tshwm sim los ntawm tus kab mob dengue (DENV), uas feem ntau kis mus rau tib neeg los ntawm kev tom los ntawm cov poj niam yoov tshaj cum, tshwj xeeb tshaj yog Aedes aegypti thiab Aedes albopictus.
Muaj plaub hom kab mob sib txawv (DENV-1, DENV-2, DENV-3, thiab DENV-4). Kev kis kab mob nrog ib qho serotype muab kev tiv thaiv mus ib txhis rau tus kab mob no tab sis tsis yog rau lwm tus.
Dengue feem ntau kis tau los ntawm yoov tshaj cum tom. Qhov tseem ceeb ntawm nws txoj kev sib kis muaj xws li:
Vector:CovAedes aegyptiyoov tshaj cum thrives nyob rau hauv nroog ib puag ncig thiab yug me nyuam nyob rau hauv stagnant dej.Aedes albopictusKuj tseem kis tau tus kab mob no tab sis tsawg dua.
Tib neeg-rau-Musquito Transmission:Thaum yoov tshaj cum tom tus neeg mob, tus kab mob nkag mus rau yoov tshaj cum thiab tuaj yeem kis mus rau lwm tus neeg tom qab lub sijhawm incubation txog li 8-12 hnub.
Vim li cas peb thiaj muaj tus mob dengue txawm nyob rau hauv cov teb chaws uas tsis yog tropical?
Kev hloov pauv huab cua: Kev kub ntxhov thoob ntiaj teb tau nthuav dav qhov chaw nyobAedes yoov tshaj cum,thawj vectors rau dengue.
Kev mus ncig thoob ntiaj teb thiab kev lag luam: Kev mus ncig thoob ntiaj teb thiab kev lag luam nce ntxiv tuaj yeem ua rau muaj kev qhia txog cov yoov tshaj cum uas muaj kab mob khaub thuas lossis cov neeg kis mus rau thaj chaw tsis muaj chaw sov.
Urbanization: Kev nrawm nrawm hauv nroog tsis muaj kev tswj dej txaus, tsim cov chaw yug me nyuam rau yoov tshaj cum.
Mosquito Adaptation: Cov yoov tshaj cum Aedes, tshwj xeebAedes aegyptithiabAedesalbopictus, tab tom hloov mus rau huab cua sov ntau ntawm cov chaw xws li thaj chaw hauv Tebchaws Europe thiab North America.
Cov xwm txheej no ua rau muaj kev sib koom ua ke kom muaj tus kab mob dengue nyob rau hauv cheeb tsam uas tsis yog tropical.
Yuav kuaj thiab kho tus mob dengue li cas?
Kev kuaj mob ntawm tus kab mob dengue tuaj yeem ua tsis yooj yim vim nws cov tsos mob tsis tshwj xeeb, uas tuaj yeem ua rau lwm yam kab mob kis.
Cov tsos mob:Thawj cov tsos mob feem ntau tshwm sim 4-10 hnub tom qab kis kab mob xws li kub taub hau, mob taub hau hnyav, mob retro-orbital, mob pob qij txha thiab leeg, pob khaus, thiab los ntshav me. Thaum muaj mob hnyav, tus mob dengue tuaj yeem ua rau tus mob dengue hemorrhagic fever (DHF) lossis dengue shock syndrome (DSS), uas tuaj yeem ua rau muaj kev phom sij rau lub neej. Kev tshawb pom ntxov pab tswj cov tsos mob ua ntej yuav mob hnyav dua.
Kev kuaj pommethods raudsib:
SKev ntsuam xyuas erology:Tshawb xyuas cov tshuaj tiv thaiv kab mob (IgM thiab IgG) tawm tsam DENV, nrog IgM qhia txog kev kis kab mob tsis ntev los no thiab IgG qhia txog kev kis yav dhau los. Cov kev ntsuam xyuas no feem ntau siv hauvchaw kho mobthiabCentralized Laboratorieskom paub meej tias cov kab mob tam sim no lossis yav dhau los thaum rov qab los lossis hauv cov neeg asymptomatic uas muaj keeb kwm raug kis.
NS1 Antigen Tests:Txheeb xyuas cov protein uas tsis yog qauv 1 (NS1) thaum lub sijhawm ntxov ntawm kev kis kab mob, ua cov cuab yeej kuaj mob thaum ntxov, zoo tagnrho rau kev kuaj pom sai hauv thawj 1-5 hnub ntawm cov tsos mob tshwm sim. Cov kev ntsuam xyuas no feem ntau ua nyob rau hauvqhov chaw kho mobxws lichaw kho mob, tsev kho mob, thiabchav haujlwm xwm txheej ceevrau kev txiav txim siab sai thiab pib kho.
NS1 + IgG/IgM Tests:Tshawb xyuas ob qho tib si nquag thiab yav dhau los kis los ntawm kev sim cov kab mob kis kab mob thiab cov tshuaj tiv thaiv kab mob hauv cov ntshav, ua rau lawv muaj txiaj ntsig zoo rau kev sib txawv ntawm cov kab mob tsis ntev los no thiab yav dhau los raug, lossis txheeb xyuas cov kab mob thib ob. Cov no feem ntau yog siv rau hauvtsev kho mob, chaw kho mob, thiabCentralized Laboratoriesrau kev ntsuam xyuas dav dav.
Kev Ntsuas Molecular:Txheeb xyuas tus kab mob RNA hauv cov ntshav, zoo tshaj plaws nyob rau hauv thawj lub lim tiam ntawm kev mob, thiab siv thaum pib kis tus kab mob kom paub meej meej, tshwj xeeb tshaj yog nyob rau hauv cov xwm txheej tseem ceeb. Cov kev xeem no feem ntau yog ua nyob rau hauvCentralized Laboratoriesnrog molecular diagnostic muaj peev xwm vim xav tau cov khoom tshwj xeeb.
Sequence:Txheeb xyuas cov khoom siv caj ces ntawm DENV los kawm txog nws cov yam ntxwv, kev hloov pauv, thiab kev hloov pauv, qhov tseem ceeb rau kev tshawb fawb txog kev kis mob, kev tshawb nrhiav tus kab mob, thiab taug qab cov kab mob hloov pauv thiab cov qauv sib kis. Qhov kev sim no tau ua hauvcov chaw tshawb fawbthiabcov chaw kuaj mob tshwj xeeb rau pej xeemrau qhov tob genomic tsom xam thiab soj ntsuam lub hom phiaj.
Tam sim no, tsis muaj kev kho mob tshwj xeeb rau tus mob dengue. Kev tswj hwm tsom mus rau kev txhawb nqa xws li kev ywg dej, kev kho mob thiab kev saib xyuas ze. Nws yuav tsum tau sau tseg tias qhov kev paub ntxov ntxov ntawm tus kab mob dengue tuaj yeem tiv thaiv tau qhov tshwm sim loj.
Macro & Micro-Test yog muab ntau yam khoom siv kuaj mob ntawm RDTs, RT-PCR thiab Sequencing rau kev kuaj pom tus mob dengue thiab saib xyuas kev sib kis:
Dengue Virus I/II/III/IV NucleicAcid Detection Kit- kua / lyophilized;
Dengue NS1 Antigen, IgM/IgG AntibodyDual Detection Kit;
HWM-FE029-Dengue NS1 Antigen Detection Kit
Dengue Virus Types 1/2/3/4 Whole Genome Enrichment Kit (Multiplex Amplification Method)
Related ntawv:
https://www.sciencedirect.com/science/article/abs/pii/S0168170218300091?via%3Dihub
Post lub sij hawm: Oct-21-2024