Lub tswv yim ntawm qog
Kab mob qog yog ib yam kab mob tshiab uas tsim los ntawm kev loj hlob tsis zoo ntawm cov cell hauv lub cev, uas feem ntau pom tias yog cov nqaij mos tsis zoo (lub qog) hauv ib feem ntawm lub cev. Kev tsim cov kab mob qog yog qhov tshwm sim ntawm kev tsis sib haum xeeb ntawm kev loj hlob ntawm cov cell raws li kev ua ntawm ntau yam kab mob qog. Kev loj hlob tsis zoo ntawm cov cell ua rau muaj kab mob qog hu ua neoplastic proliferation.
Xyoo 2019, Cancer Cell tau tshaj tawm ib tsab xov xwm tsis ntev los no. Cov kws tshawb fawb pom tias metformin tuaj yeem tiv thaiv kev loj hlob ntawm qog nqaij hlav thaum lub sijhawm yoo mov, thiab tau hais tias PP2A-GSK3β-MCL-1 txoj kev yuav yog lub hom phiaj tshiab rau kev kho mob qog nqaij hlav.
Qhov txawv tseem ceeb ntawm qog nqaij hlav benign thiab qog nqaij hlav malignant
Mob qog nqaij hlav zoo: loj hlob qeeb, lub hau me me, o tuaj, swb mus kov, ciam teb meej, tsis muaj metastasis, feem ntau zoo prognosis, cov tsos mob hauv zos, feem ntau tsis muaj tag nrho lub cev, feem ntau tsis ua rau cov neeg mob tuag.
Mob qog nqaij hlav (mob qog): loj hlob sai, loj hlob mus rau sab nraud, lo rau cov nqaij ib puag ncig, tsis muaj peev xwm txav mus los thaum kov, ciam teb tsis meej, yooj yim kis mus rau lwm qhov, yooj yim rov qab los tom qab kho, kub taub hau me ntsis, tsis xav noj mov thaum ntxov, poob phaus, qaug zog heev, ntshav tsis txaus thiab kub taub hau thaum kawg, thiab lwm yam. Yog tias tsis kho raws sijhawm, feem ntau nws ua rau tuag.
Vim tias cov qog nqaij hlav tsis muaj mob thiab cov qog nqaij hlav phem tsis yog tsuas muaj cov tsos mob sib txawv xwb, tab sis qhov tseem ceeb tshaj, lawv qhov kev kwv yees txawv, yog li thaum koj pom ib lub qog hauv koj lub cev thiab cov tsos mob saum toj no, koj yuav tsum nrhiav kev pab kho mob raws sijhawm.
Kev kho mob qog nqaij hlav rau tus kheej
Kev Tshawb Fawb Txog Tib Neeg Lub Cev thiab Kev Tshawb Fawb Txog Kab Mob Cancer Thoob Ntiaj Teb
Lub Hom Phiaj Tshawb Fawb Txog Tib Neeg (Human Genome Project), uas tau pib ua haujlwm hauv Tebchaws Meskas xyoo 1990, lub hom phiaj yog qhib tag nrho cov lej ntawm kwv yees li 100,000 lub noob caj noob ces hauv tib neeg lub cev thiab kos cov spectrum ntawm tib neeg cov noob caj noob ces.
Xyoo 2006, qhov International Cancer Genome Project, uas tau koom ua ke los ntawm ntau lub tebchaws, yog lwm qhov kev tshawb fawb tseem ceeb tom qab Human Genome Project.
Cov teeb meem tseem ceeb hauv kev kho mob qog nqaij hlav
Kev kuaj mob thiab kev kho mob rau tus kheej = Kev kuaj mob rau tus kheej + cov tshuaj uas tsom rau tus kheej
Rau feem ntau cov neeg mob sib txawv uas raug kev txom nyem los ntawm tib yam kab mob, txoj kev kho mob yog siv tib yam tshuaj thiab tib qho koob tshuaj, tab sis qhov tseeb, cov neeg mob sib txawv muaj qhov sib txawv ntawm cov txiaj ntsig kho mob thiab cov kev tsis zoo, thiab qee zaum qhov sib txawv no tuaj yeem ua rau tuag taus.
Kev kho mob siv tshuaj tsom rau cov neeg mob muaj cov yam ntxwv ntawm kev xaiv tua cov hlwb qog nqaij hlav yam tsis tua lossis tsis tshua muaj kev puas tsuaj rau cov hlwb ib txwm muaj, nrog rau cov kev phiv me me, uas ua rau lub neej zoo dua thiab cov txiaj ntsig kho mob ntawm cov neeg mob zoo dua.
Vim tias kev kho mob tsom mus rau tus neeg mob yog tsim los tawm tsam cov tshuaj tshwj xeeb, nws yog qhov tsim nyog los nrhiav cov noob caj noob ces ntawm cov qog nqaij hlav thiab nrhiav seb cov neeg mob puas muaj cov hom phiaj sib xws ua ntej noj tshuaj, kom nws thiaj li kho tau zoo.
Kev kuaj pom cov noob caj noob ces ntawm cov qog nqaij hlav
Kev nrhiav pom cov noob caj noob ces ntawm cov qog nqaij hlav yog ib txoj kev los tshuaj xyuas thiab txheeb xyuas cov DNA/RNA ntawm cov qe ntshav qog.
Qhov tseem ceeb ntawm kev kuaj pom cov noob caj noob ces ntawm cov qog nqaij hlav yog los coj kev xaiv tshuaj kho mob (cov tshuaj uas tsom mus rau tus neeg mob, cov tshuaj tiv thaiv kab mob thiab lwm yam kab mob AIDS tshiab, kev kho mob lig), thiab los kwv yees qhov kev kwv yees thiab kev rov tshwm sim dua.
Cov kev daws teeb meem los ntawm Acer Macro & Micro-Test
Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv ntawm Tib Neeg EGFR Gene 29 (Fluorescence PCR))
Siv rau kev kuaj pom zoo ntawm cov kev hloov pauv feem ntau hauv exon 18-21 ntawm EGFR gene hauv cov neeg mob qog nqaij hlav ntsws uas tsis yog me me hauv vitro.
1. Kev qhia txog kev tswj xyuas zoo sab hauv hauv lub kaw lus tuaj yeem saib xyuas cov txheej txheem sim thiab xyuas kom meej qhov zoo ntawm kev sim.
2. Kev rhiab heev: tus nqi hloov pauv ntawm 1% tuaj yeem pom tau ruaj khov hauv keeb kwm yav dhau los ntawm 3ng / μL cov tshuaj tiv thaiv nucleic acid qus.
3. Kev tshwj xeeb siab: tsis muaj kev sib xyaw nrog cov txiaj ntsig ntawm kev kuaj pom ntawm cov noob caj noob ces tib neeg qus thiab lwm hom kev hloov pauv.
KRAS 8 Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv (Fluorescence PCR)
Yim hom kev hloov pauv hauv codons 12 thiab 13 ntawm K-ras gene siv rau kev kuaj pom zoo ntawm DNA rho tawm los ntawm tib neeg cov paraffin-embedded pathological seem hauv vitro.
1. Kev qhia txog kev tswj xyuas zoo sab hauv hauv lub kaw lus tuaj yeem saib xyuas cov txheej txheem sim thiab xyuas kom meej qhov zoo ntawm kev sim.
2. Kev rhiab heev: tus nqi hloov pauv ntawm 1% tuaj yeem pom tau ruaj khov hauv keeb kwm yav dhau los ntawm 3ng / μL cov tshuaj tiv thaiv nucleic acid qus.
3. Kev tshwj xeeb siab: tsis muaj kev sib xyaw nrog cov txiaj ntsig ntawm kev kuaj pom ntawm cov noob caj noob ces tib neeg qus thiab lwm hom kev hloov pauv.
Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv ntawm Human ROS1 Fusion Gene (Fluorescence PCR)
Siv los nrhiav kom tau 14 hom kev hloov pauv ntawm ROS1 fusion gene hauv cov neeg mob qog nqaij hlav ntsws uas tsis yog me me hauv vitro.
1. Kev qhia txog kev tswj xyuas zoo sab hauv hauv lub kaw lus tuaj yeem saib xyuas cov txheej txheem sim thiab xyuas kom meej qhov zoo ntawm kev sim.
2. Kev rhiab heev: 20 daim ntawv theej ntawm kev hloov pauv fusion.
3. Kev tshwj xeeb siab: tsis muaj kev sib xyaw nrog cov txiaj ntsig ntawm kev kuaj pom ntawm cov noob caj noob ces tib neeg qus thiab lwm hom kev hloov pauv.
Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv ntawm Tib Neeg EML4-ALK Fusion Gene (Fluorescence PCR)
Siv los nrhiav kom tau 12 hom kev hloov pauv ntawm EML4-ALK fusion gene hauv cov neeg mob qog nqaij hlav ntsws uas tsis yog me me hauv vitro.
1. Kev qhia txog kev tswj xyuas zoo sab hauv hauv lub kaw lus tuaj yeem saib xyuas cov txheej txheem sim thiab xyuas kom meej qhov zoo ntawm kev sim.
2. Kev rhiab heev: 20 daim ntawv theej ntawm kev hloov pauv fusion.
3. Kev tshwj xeeb siab: tsis muaj kev sib xyaw nrog cov txiaj ntsig ntawm kev kuaj pom ntawm cov noob caj noob ces tib neeg qus thiab lwm hom kev hloov pauv.
Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv ntawm Tib Neeg BRAF Gene V600E (Fluorescence PCR)
Nws yog siv los nrhiav qhov kev hloov pauv ntawm BRAF gene V600E hauv cov qauv ntaub so ntswg paraffin-embedded ntawm tib neeg melanoma, mob qog nqaij hlav colorectal, mob qog nqaij hlav thyroid thiab mob qog nqaij hlav ntsws hauv vitro.
1. Kev qhia txog kev tswj xyuas zoo sab hauv hauv lub kaw lus tuaj yeem saib xyuas cov txheej txheem sim thiab xyuas kom meej qhov zoo ntawm kev sim.
2. Kev rhiab heev: tus nqi hloov pauv ntawm 1% tuaj yeem pom tau ruaj khov hauv keeb kwm yav dhau los ntawm 3ng / μL cov tshuaj tiv thaiv nucleic acid qus.
3. Kev tshwj xeeb siab: tsis muaj kev sib xyaw nrog cov txiaj ntsig ntawm kev kuaj pom ntawm cov noob caj noob ces tib neeg qus thiab lwm hom kev hloov pauv.
| Khoom No. | Lub Npe Khoom | Cov Lus Qhia Tshwj Xeeb |
| HWTS-TM006 | Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv ntawm Tib Neeg EML4-ALK Fusion Gene (Fluorescence PCR) | 20 qhov kev kuaj/pawg khoom siv 50 qhov kev kuaj/pawg khoom siv |
| HWTS-TM007 | Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv ntawm Tib Neeg BRAF Gene V600E (Fluorescence PCR) | 24 qhov kev sim/pawg khoom siv 48 qhov kev kuaj/pawg khoom siv |
| HWTS-TM009 | Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv ntawm Human ROS1 Fusion Gene (Fluorescence PCR) | 20 qhov kev kuaj/pawg khoom siv 50 qhov kev kuaj/pawg khoom siv |
| HWTS-TM012 | Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv ntawm Tib Neeg EGFR Gene 29 (Fluorescence PCR)) | 16 qhov kev sim/pawg khoom siv 32 qhov kev kuaj/pawg khoom siv |
| HWTS-TM014 | KRAS 8 Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv (Fluorescence PCR) | 24 qhov kev sim/pawg khoom siv 48 qhov kev kuaj/pawg khoom siv |
| HWTS-TM016 | Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv ntawm Tib Neeg TEL-AML1 Fusion Gene (Fluorescence PCR) | 24 qhov kev sim/pawg khoom siv |
| HWTS-GE010 | Cov Khoom Siv Tshawb Nrhiav Kev Hloov Pauv ntawm Cov noob caj noob ces BCR-ABL rau Tib Neeg (Fluorescence PCR) | 24 qhov kev sim/pawg khoom siv |
Lub sijhawm tshaj tawm: Plaub Hlis-17-2024