Lub tswvyim ntawm qog
Cov qog nqaij hlav yog ib yam kabmob tshiab uas tsim los ntawm qhov txawv txav ntawm cov hlwb hauv lub cev, uas feem ntau tshwm sim raws li qhov txawv txav ntawm cov ntaub so ntswg loj (loj) hauv ib cheeb tsam ntawm lub cev. Cov qog tsim tawm yog tshwm sim los ntawm kev tsis sib haum xeeb loj ntawm kev loj hlob ntawm tes raws li kev ua ntawm ntau yam qog nqaij hlav. Kev loj hlob txawv txav ntawm cov hlwb uas ua rau qog nqaij hlav hu ua neoplastic proliferation.
Hauv 2019, Cancer Cell luam tawm ib tsab xov xwm tsis ntev los no. Cov kws tshawb fawb pom tias metformin tuaj yeem cuam tshuam cov qog loj hlob hauv lub xeev yoo mov, thiab qhia tias PP2A-GSK3β-MCL-1 txoj hauv kev yuav yog lub hom phiaj tshiab rau kev kho mob qog noj ntshav.
Lub ntsiab sib txawv ntawm benign qog thiab malignant qog
Cov qog nqaij hlav zoo: kev loj hlob qeeb, tshuaj ntsiav, kev loj hlob o, zawv zawg mus rau qhov kov, thaj tsam ntshiab, tsis muaj metastasis, feem ntau pom zoo, cov tsos mob hauv zos compression, feem ntau tsis muaj tag nrho lub cev, feem ntau tsis ua rau cov neeg mob tuag.
Malignant qog (mob cancer): kev loj hlob sai, invasive loj hlob, adhesion rau ib puag ncig cov ntaub so ntswg, tsis muaj peev xwm txav tau thaum kov, tsis paub meej ciam teb, yooj yim metastasis, yooj yim rov tshwm sim tom qab kev kho mob, ua npaws, tsis qab los noj mov nyob rau hauv thaum ntxov theem, poob phaus, hnyav emaciation, anemia thiab kub taub hau nyob rau hauv lub lig theem, thiab lwm yam. Yog hais tias tsis kho nyob rau hauv lub sij hawm, nws feem ntau ua rau tuag.
"Vim tias cov qog nqaij hlav zoo thiab cov qog nqaij hlav tsis yog tsuas yog muaj cov tsos mob sib txawv, tab sis qhov tseem ceeb tshaj, lawv qhov kev mob tshwm sim txawv, yog li thaum koj pom ib pob hauv koj lub cev thiab cov tsos mob saum toj no, koj yuav tsum nrhiav kev kho mob raws sij hawm."
Kev kho tus kheej ntawm cov qog
Human Genome Project thiab International Cancer Genome Project
Human Genome Project, uas tau tsim tawm hauv Tebchaws Meskas hauv xyoo 1990, lub hom phiaj los qhib tag nrho cov lej ntawm 100,000 cov noob hauv tib neeg lub cev thiab kos cov spectrum ntawm tib neeg cov noob.
Xyoo 2006, International Cancer Genome Project, koom ua ke los ntawm ntau lub teb chaws, yog lwm qhov kev tshawb fawb loj tom qab Human Genome Project.
Cov teeb meem tseem ceeb hauv kev kho mob qog
Kev kuaj mob tus kheej thiab kev kho tus kheej = Kev kuaj mob tus kheej + tshuaj tsom
Rau cov neeg mob sib txawv feem ntau raug kev txom nyem los ntawm tib tus kab mob, txoj kev kho mob yog siv cov tshuaj tib yam thiab cov qauv siv tshuaj, tab sis qhov tseeb, cov neeg mob sib txawv muaj qhov sib txawv ntawm kev kho mob thiab kev tsis zoo, thiab qee zaum qhov sib txawv no tseem ua rau tuag taus.
Targeted drug therapy muaj cov yam ntxwv ntawm kev xaiv tua cov qog hlwb yam tsis tau tua lossis tsuas yog tsis tshua muaj kev puas tsuaj rau cov hlwb, nrog rau cov kev mob tshwm sim me me, uas ua rau muaj txiaj ntsig zoo ntawm lub neej thiab kev kho mob ntawm cov neeg mob.
Vim tias cov phiaj xwm kev kho mob yog tsim los tawm tsam cov hom phiaj tshwj xeeb, nws yog ib qho tsim nyog los tshawb xyuas cov noob caj noob ces thiab xyuas seb cov neeg mob puas muaj cov hom phiaj sib xws ua ntej noj tshuaj, txhawm rau ua kom nws cov nyhuv curative.
Kev kuaj mob qog nqaij hlav
Kev kuaj mob qog nqaij hlav yog ib txoj hauv kev los txheeb xyuas thiab ua raws DNA / RNA ntawm cov qog hlwb.
Qhov tseem ceeb ntawm kev tshawb nrhiav qog noob caj noob ces yog los coj cov kev xaiv tshuaj ntawm cov tshuaj kho mob (cov tshuaj tiv thaiv, tshuaj tiv thaiv kab mob tiv thaiv kab mob thiab lwm yam AIDS tshiab, kev kho mob lig), thiab txhawm rau kwv yees qhov tshwm sim thiab rov tshwm sim.
Cov kev daws teeb meem muab los ntawm Acer Macro & Micro-Test
Tib neeg EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR)
Siv rau kev kuaj pom zoo ntawm kev hloov pauv hauv exon 18-21 ntawm EGFR noob hauv tib neeg cov neeg mob qog nqaij hlav qog nqaij hlav hauv vitro.
1. Kev taw qhia txog kev tswj hwm kev tswj hwm zoo hauv lub cev tuaj yeem saib xyuas cov txheej txheem sim thiab xyuas kom muaj kev sim zoo.
2. Siab rhiab heev: qhov kev hloov pauv ntawm 1% tuaj yeem kuaj tau ruaj khov hauv keeb kwm yav dhau los ntawm 3ng / μL qus-hom nucleic acid tshuaj tiv thaiv.
3. Qhov tshwj xeeb siab: tsis muaj qhov cuam tshuam nrog kev tshawb pom ntawm cov tsiaj qus-hom tib neeg genomic DNA thiab lwm hom mutant.
KRAS 8 Mutations Detection Kit (Fluorescence PCR)
Yim hom kev hloov pauv hauv codons 12 thiab 13 ntawm K-ras gene siv rau kev tshawb pom zoo ntawm DNA muab rho tawm los ntawm tib neeg paraffin-embedded pathological seem hauv vitro.
1. Kev taw qhia txog kev tswj hwm kev tswj hwm zoo hauv lub cev tuaj yeem saib xyuas cov txheej txheem sim thiab xyuas kom muaj kev sim zoo.
2. Siab rhiab heev: qhov kev hloov pauv ntawm 1% tuaj yeem kuaj tau ruaj khov hauv keeb kwm yav dhau los ntawm 3ng / μL qus-hom nucleic acid tshuaj tiv thaiv.
3. Qhov tshwj xeeb siab: tsis muaj qhov cuam tshuam nrog kev tshawb pom ntawm cov tsiaj qus-hom tib neeg genomic DNA thiab lwm hom mutant.
Human ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Siv los txheeb xyuas 14 yam hloov pauv ntawm ROS1 fusion gene hauv tib neeg uas tsis yog me me ntawm lub ntsws qog noj ntshav hauv vitro.
1. Kev taw qhia txog kev tswj hwm kev tswj hwm zoo hauv lub cev tuaj yeem saib xyuas cov txheej txheem sim thiab xyuas kom muaj kev sim zoo.
2. High rhiab heev: 20 daim ntawv luam ntawm fusion mutation.
3. Qhov tshwj xeeb siab: tsis muaj qhov cuam tshuam nrog kev tshawb pom ntawm cov tsiaj qus-hom tib neeg genomic DNA thiab lwm hom mutant.
Human EML4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Siv los txheeb xyuas 12 qhov kev hloov pauv ntawm EML4-ALK fusion noob hauv tib neeg cov neeg mob qog nqaij hlav qog nqaij hlav me me hauv vitro.
1. Kev taw qhia txog kev tswj hwm kev tswj hwm zoo hauv lub cev tuaj yeem saib xyuas cov txheej txheem sim thiab xyuas kom muaj kev sim zoo.
2. High rhiab heev: 20 daim ntawv luam ntawm fusion mutation.
3. Qhov tshwj xeeb siab: tsis muaj qhov cuam tshuam nrog kev tshawb pom ntawm cov tsiaj qus-hom tib neeg genomic DNA thiab lwm hom mutant.
Tib neeg BRAF Gene V600E Mutation Detection Kit (Fluorescence PCR)
Nws yog siv los txheeb xyuas qhov kev hloov pauv ntawm BRAF gene V600E hauv paraffin-embedded cov ntaub so ntswg ntawm tib neeg melanoma, mob qog noj ntshav, qog nqaij hlav qog noj ntshav thiab mob ntsws cancer hauv vitro.
1. Kev taw qhia txog kev tswj hwm kev tswj hwm zoo hauv lub cev tuaj yeem saib xyuas cov txheej txheem sim thiab xyuas kom muaj kev sim zoo.
2. Siab rhiab heev: qhov kev hloov pauv ntawm 1% tuaj yeem kuaj tau ruaj khov hauv keeb kwm yav dhau los ntawm 3ng / μL qus-hom nucleic acid tshuaj tiv thaiv.
3. Qhov tshwj xeeb siab: tsis muaj qhov cuam tshuam nrog kev tshawb pom ntawm cov tsiaj qus-hom tib neeg genomic DNA thiab lwm hom mutant.
| Yam khoom No | Khoom npe | Specification |
| HWM-TM006 | Human EML4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 20 xeem/kit 50 test/kit |
| HWM-TM007 | Tib neeg BRAF Gene V600E Mutation Detection Kit (Fluorescence PCR) | 24 xeem/kit 48 xeem/kit |
| HWM-TM009 | Human ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 20 xeem/kit 50 test/kit |
| HWM-TM012 | Tib neeg EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR) | 16 test/kit 32 test/kit |
| HWM-TM014 | KRAS 8 Mutations Detection Kit (Fluorescence PCR) | 24 xeem/kit 48 xeem/kit |
| HWM-TM016 | Tib neeg TEL-AML1 Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 24 xeem/kit |
| HWM-GE010 | Tib neeg BCR-ABL Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 24 xeem/kit |
Post lub sij hawm: Apr-17-2024