Lub Tsib Hlis 17, 2023 yog 19th "World Hypertension Day".
Ntshav siab yog hu ua "killer" ntawm tib neeg kev noj qab haus huv.Ntau tshaj li ib nrab ntawm cov kab mob plawv, mob stroke thiab lub plawv tsis ua haujlwm yog tshwm sim los ntawm kev kub siab.Yog li ntawd, peb tseem muaj txoj hauv kev ntev mus rau hauv kev tiv thaiv thiab kev kho mob ntshav siab.
01 Ntiaj teb no nthuav dav ntawm kev kub siab
Thoob plaws ntiaj teb, kwv yees li 1.28 billion tus neeg laus hnub nyoog 30-79 raug mob ntshav siab.Tsuas yog 42% ntawm cov neeg mob ntshav siab tau kuaj pom thiab kho, thiab kwv yees li ib ntawm tsib tus neeg mob tau tswj hwm lawv cov ntshav siab.Xyoo 2019, cov neeg tuag los ntawm kev kub siab thoob ntiaj teb tau tshaj 10 lab, suav txog li 19% ntawm tag nrho cov neeg tuag.
02 Ntshav Qab Zib yog dab tsi?
Kev kub siab yog ib qho kev kho mob plawv uas tshwm sim los ntawm cov ntshav siab tsis tu ncua hauv cov hlab ntsha.
Cov neeg mob feem ntau tsis muaj cov tsos mob pom tseeb lossis cov tsos mob tshwm sim.Qee tus neeg mob ntshav siab me me yuav muaj kiv taub hau, qaug zog lossis los ntshav.Qee cov neeg mob uas muaj ntshav siab systolic ntawm 200mmHg lossis siab dua yuav tsis muaj qhov pom tseeb hauv kev kho mob, tab sis lawv lub plawv, hlwb, lub raum thiab cov hlab ntsha tau raug puas tsuaj rau qee yam.Raws li tus kab mob no zuj zus, cov kab mob uas ua rau lub neej tsis zoo xws li lub plawv tsis ua haujlwm, myocardial infarction, cerebral hemorrhage, cerebral infarction, lub raum tsis txaus, uremia, thiab peripheral vascular occlusion yuav tshwm sim.
(1) Qhov tseem ceeb kub siab: suav txog li 90-95% ntawm cov neeg mob ntshav siab.Nws tuaj yeem cuam tshuam nrog ntau yam xws li caj ces, kev ua neej, kev rog, kev ntxhov siab thiab hnub nyoog.
(2) Secondary hypertension: suav txog li 5-10% ntawm cov neeg mob ntshav siab.Nws yog kev nce ntshav siab los ntawm lwm yam kab mob lossis tshuaj, xws li kab mob raum, kab mob endocrine, kab mob plawv, tshuaj phiv, thiab lwm yam.
03 Tshuaj kho mob rau cov neeg mob ntshav siab
Cov ntsiab cai ntawm kev kho mob ntshav siab yog: noj tshuaj kom ntev, tswj cov ntshav siab, txhim kho cov tsos mob, tiv thaiv thiab tswj cov teeb meem, thiab lwm yam. Cov kev kho mob suav nrog kev txhim kho txoj kev ua neej, kev tswj tus kheej ntawm cov ntshav siab, thiab kev tswj cov kab mob plawv, cov uas Kev siv cov tshuaj antihypertensive mus sij hawm ntev yog qhov kev ntsuas tseem ceeb tshaj plaws.
Cov kws kho mob feem ntau xaiv kev sib xyaw ntawm cov tshuaj sib txawv raws li qib ntshav siab thiab tag nrho cov kab mob plawv ntawm tus neeg mob, thiab muab cov tshuaj kho mob kom ua tiav kev tswj ntshav siab.Cov tshuaj antihypertensive siv los ntawm cov neeg mob xws li angiotensin-hloov enzyme inhibitors (ACEI), angiotensin receptor blockers (ARB), β-blockers, calcium channel blockers (CCB), thiab diuretics.
04 Kev ntsuam xyuas caj ces rau kev siv tshuaj ib leeg rau cov neeg mob ntshav siab
Tam sim no, cov tshuaj antihypertensive niaj hnub siv hauv kev kho mob feem ntau muaj qhov sib txawv ntawm tus kheej, thiab cov nyhuv curative ntawm cov tshuaj ntshav siab muaj feem cuam tshuam nrog genetic polymorphisms.Pharmacogenomics tuaj yeem qhia meej txog kev sib raug zoo ntawm tus kheej cov lus teb rau cov tshuaj thiab kev hloov pauv caj ces, xws li cov nyhuv curative, qib ntau npaum li cas thiab cov tshuaj tiv thaiv tsis zoo tos.Cov kws kho mob txheeb xyuas cov hom phiaj muaj feem cuam tshuam nrog kev tswj ntshav siab hauv cov neeg mob tuaj yeem pab kho cov tshuaj.
Yog li, kev tshawb nrhiav cov tshuaj muaj feem xyuam nrog cov noob caj noob ces tuaj yeem muab cov pov thawj muaj feem cuam tshuam rau kev kuaj mob ntawm cov tshuaj tsim nyog thiab cov tshuaj noj, thiab txhim kho kev nyab xeeb thiab kev siv tshuaj zoo.
05 Cov pej xeem siv tau rau kev kuaj caj ces ntawm tus kheej cov tshuaj rau ntshav siab
(1) Cov neeg mob ntshav siab
(2) Cov neeg muaj keeb kwm ntawm tsev neeg muaj ntshav siab
(3) Cov neeg uas muaj kev phiv tshuaj tsis zoo
(4) Cov neeg uas muaj kev kho mob tsis zoo
(5) Cov neeg uas yuav tsum tau noj ntau yam tshuaj tib lub sijhawm
06 Kev daws teeb meem
Macro & Micro-Test tau tsim ntau yam khoom siv tshuaj fluorescence rau kev taw qhia thiab tshawb xyuas cov tshuaj tiv thaiv kab mob siab, muab kev daws teeb meem tag nrho rau kev taw qhia cov tshuaj kho mob ib tus neeg thiab ntsuas qhov kev pheej hmoo ntawm cov tshuaj tiv thaiv tsis zoo:
Cov khoom lag luam tuaj yeem tshawb pom 8 gene loci ntsig txog cov tshuaj tiv thaiv kev mob ntshav siab thiab sib txuas 5 cov chav kawm loj ntawm cov tshuaj (B adrenergic receptor blockers, angiotensin II receptor antagonists, angiotensin converting enzyme inhibitors, Calcium antagonists thiab diuretics), ib qho tseem ceeb cov cuab yeej uas tuaj yeem coj cov tshuaj kho mob rau tus kheej. thiab ntsuas qhov kev pheej hmoo ntawm cov tshuaj tiv thaiv tsis zoo.Los ntawm kev txheeb xyuas cov tshuaj metabolizing enzymes thiab cov tshuaj lub hom phiaj cov noob, cov kws kho mob tuaj yeem raug coj los xaiv cov tshuaj antihypertensive tsim nyog thiab ntau npaum li cas rau cov neeg mob tshwj xeeb, thiab txhim kho kev ua tau zoo thiab kev nyab xeeb ntawm kev kho tshuaj antihypertensive.
Yooj yim rau siv: siv tshuab melting nkhaus, 2 qhov dej tshuaj tiv thaiv tuaj yeem ntes 8 qhov chaw.
Siab rhiab heev: qhov ntsuas qis tshaj plaws yog 10.0ng / μL.
Siab raug: Tag nrho ntawm 60 tus qauv raug kuaj, thiab SNP qhov chaw ntawm txhua lub noob tau zoo raws li cov txiaj ntsig ntawm kev sib txuas ntawm cov tiam tom ntej lossis thawj tiam thib ob, thiab qhov kev kuaj pom tau zoo yog 100%.
Kev ntseeg tau: Sab hauv tus qauv kev tswj xyuas zoo tuaj yeem saib xyuas tag nrho cov txheej txheem tshawb nrhiav.
Post lub sij hawm: May-17-2023