Tib Neeg BCR-ALL Fusion Gene Gene
Khoom npe
HWTS-ge010a-tib neeg BCR-ABL fusion gene mution cov mution nrhiav khoom siv (fluorescence pcr)
HWTS-Ge016A-khov-qhuav-qhuav tib neeg BCR-ABL fusion gene mution Cov khoom siv hloov kho (fluorescence pcr)
Kev kawm
Mob Myelogenouslexemia (CML) yog tus kab mob malignant ntawm hematopoietic qia hlwb. Ntau tshaj 95% ntawm CML cov neeg mob nqa lub Philadelphia chromosome (Ph) hauv lawv cov ntshav hlwb. Feem ntau pathogenesis ntawm CML yog raws li hauv qab no: BR-ABL fusion gene yog tsim los ntawm ib tug qauv ntawm chromosome 9 (9q34) thiab cov pawg Breakpoint pawg ( BCR) gene nyob ntawm caj npab ntev ntawm chromosome 22 (22q11); Cov fusion protein enreed los ntawm cov gene no muaj Tyrosine Kinase (xws li ras, thiab jak / stats proliferate malospifant, thiab yog li ua qhov tshwm sim ntawm cml. BCR-ABL yog ib qho ntawm cov ntsuas tseem ceeb ntawm cml. Qhov kev hloov pauv zoo ntawm nws cov kev hloov pauv qib yog qhov qhia tau meej rau cov kev txiav txim siab prenogrogia thiab tuaj yeem siv los twv seb cov ntshav ntswg tom qab kho mob.
Tshooj
| Tshaib plab | BR-ABL FUSTE GENE |
| Vic / hex | Sab hauv tswj |
Kev tsis muaj
| Chaw ntim khoom | Cov kua: ≤-18 ℃ hauv kev tsaus ntuj |
| Txee-Lub Neej | Cov kua: 9 lub hlis |
| Zauv Hom | Cov Pwm Xob Pob Txuam |
| Lub lab | 1000 daim ntawv luam / ml |
| Yam tshwj xeeb
| Tsis muaj tus ntoo khaub lig-reactivity nrog lwm cov fusion genes tel-aml1, mll-af4, AML1-ETO, thiab PML-Rara |
| Muaj cov cuab yeej siv tau | Siv biosystems 7500 REO-lub sijhawm PRR cov tshuab Siv biosystems 7500 ceev real-sijhawm pc tshuab Quatstudio® 5 REO-lub sijhawm PRR TSHUAB Slan-96p ROOST-SICTICE PRRY Lightcycler ®480 REO-SIJHAWM PCR system LINEGENE 9600 PLUS ROOST-LUB SIJ HAWM-LUB CEV Ma-6000 tiag tiag-lub sij hawm pestitive thermal cycler Biorad Cfx96 REO-SIJHAWM PCR system Biorad Cfx Open 96 Real-Time Pricr System |
