Tib neeg CYP2C19 Gene Polymorphism
Khoom npe
HWTS-Ge012A-tib neeg CYP2C19 Gene Polymorphism nrhiav khoom siv (fluorescence pcr)
Daim ntawv muaj cai
CE / TFDA
Kev kawm
CYP2C19 yog ib qho ntawm cov tshuaj uas tseem ceeb tso tawm tshuaj metabolizing hauv cy450 tsev neeg. Ntau yam endogenous substrates thiab kwv yees li 2% ntawm cov tshuaj tua kab mob antipdelants (omeponvulss kuj tseem muaj qhov sib txawv ntawm cov peev xwm metabolizing ntawm muaj feem xyuam tshuaj. Cov kev hloov pauv no ntawm * 2 (Rs424285) thiab * 3 (RS4986893) ua rau kom poob ntawm MetR2C19 Gene encoded los ntawm CYR2C193) Ua rau cov ntshav sib xyaw ua ke, thiab ua rau cov tshuaj tiv thaiv cuam tshuam nrog ntshav siab. * 17 (RS12248560) Yuav ua rau cov haujlwm enzyme tuaj yeem encoded los ntawm CyP2C19 gene, kev txhim kho cov kev sib thab platelet, thiab txhim kho cov platelet sib deev Rau cov tib neeg nrog qeeb metabolism hauv cov tshuaj, kev noj tshuaj ntev ntev yuav ua rau muaj kev puas tsuaj rau kev puas tsuaj rau kev puas tsuaj rau kev puas tsuaj rau kev puas tsuaj rau kev puas tsuaj rau kev puas tsuaj, hematoplotic kev puas tsuaj, thiab lwm yam tuaj yeem ua rau tuag taus. Raws li tus kheej qhov sib txawv hauv cov tshuaj metabolism hauv plaub, nws feem ntau muab faib ua plaub qhov kev ua haujlwm nrawm dua (um, ), Nruab Nrab Metabolism (IM, * 1 / * 1 / * 3), qeeb metabolism (PM, * 2 / * 3, * 3 / * 3).
Tshooj
| Tshaib plab | CYP2C19 * 2 |
| Cy5 | CYP2C9 * 3 |
| Nas | CYP2C19 * 17 |
| Vic / hex | IC |
Kev tsis muaj
| Chaw ntim khoom | Cov kua: ≤-18 ℃ |
| Txee-Lub Neej | 12 lub hlis |
| Zauv Hom | Fresh Edta Anticoagulated Ntshav |
| CV | APR5.0% |
| Lub lab | 1.0ng / μl |
| Yam tshwj xeeb | Tsis muaj tus ntoo khaub lig-reactivity nrog lwm cov kev sib txawv heev (CYP2C9 Gene) hauv tib neeg genome. Kev sib hloov ntawm CYP2C19 * 23, CYP2C19 * 25 thiab CYP2C19 * 25 Cov chaw nyob sab nraud ntawm cov khoom siv no tau cuam tshuam ntawm cov txiaj ntsig ntawm cov khoom siv no. |
| Muaj cov cuab yeej siv tau | Siv biosystems 7500 REO-lub sijhawm PRR cov tshuab Siv biosystems 7500 ceev real-sijhawm pc tshuab QuatStudio®5 Real-sijhawm PRR cov tshuab Slan-96p ROOST-SICTICE PRRY Lightcycler ®480 REO-SIJHAWM PCR system LINEGENE 9600 PLUS ROOST-LUB SIJ HAWM-LUB CEV Ma-6000 tiag tiag-lub sij hawm pestitive thermal cycler Biorad Cfx96 REO-SIJHAWM PCR system Biorad Cfx Open 96 Real-Time Pricr System |
Ua Haujlwm Ntws
Pom zoo rho tawm reagent: Macro & Cov khoom siv Rwg acid Extraction (HWTS-301) Co., Ltd. cov kev rho tawm yuav tsum muab rho tawm raws li cov lus qhia. Cov qauv rho tawm ntim tau 200μL, thiab cov lus pom zoo kom pom zoo kom meej yog 100μL.
Pom zoo rho tawm reagent: Wizard® Groomic Cov Khoom Siv (cov catalog Yuav tsum tau muab rho tawm raws li cov lus qhia rho tawm, thiab cov lus pom zoo yuav tsum muaj zog muaj 200 μl thiab cov lus pom zoo kom pom zoo tau 160 μl.
