Kras 8 Hloov Siab

Taw qhia kev hloov pauv hauv Kras noob tau pom nyob rau hauv ib tug xov tooj ntawm tib neeg cov qog nqaij tawv, txog 17%% hloov kho mob ntsws cancer, 20% Cov neeg mob. Vim tias P21 Protein envoded los ntawm K-Ras Gene nyob hauv qab ntawm EggFr Kev Nkag Mus rau hauv Pathwing, tom qab K-Ras Genetrated cov tshuaj ntawm EGFR, ua rau txuas ntxiv malignant proliferation ntawm cov hlwb. Kev sib hloov hauv cov gene cov gene feem ntau conferars cov neeg mob ntsws cancer thiab cov tshuaj tiv thaiv kab mob EGFLY rau hauv cov neeg mob qog nqaij hlav cancer. In 2008, the National Comprehensive Cancer Network (NCCN) issued a clinical practice guideline for colorectal cancer, which pointed out that the mutation sites that cause K-ras to be activated are mainly located in codons 12 and 13 of exon 2, and recommended that Txhua tus neeg mob uas tau txais cov kabmob Cancera Colorastatic Cancer tuaj yeem kuaj rau K-Ras sib hloov ua ntej kev kho mob. Yog li ntawd, kev tshawb nrhiav tau sai thiab yog qhov tseem ceeb ntawm kev coj ua tshuaj xyuas cov chaw kuaj mob. Cov cuab yeej siv no siv DNA raws li kev kuaj pom kom muab kev ntsuas mob qog noj ntshav, mob ntsws uas tau txais txiaj ntsig los ntawm cov tshuaj tiv thaiv kab mob. Cov khoom siv ntsuas ntawm cov khoom siv yog rau kev soj ntsuam siv xwb thiab yuav tsum tsis txhob siv los ua ib qho kev kho mob rau tus kheej. Cov kws kho mob yuav tsum tau txiav txim siab rau cov txiaj ntsig kev kuaj mob raws li cov neeg mob, kev kho yeeb yam tshuaj, kev kho mob thiab lwm yam kev kuaj sim.