● Mycobacterium Tuberculosis
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Mycobacterium Tuberculosis Nucleic Acid thiab Rifampicin (RIF), Resistance (INH)
Cov khoom siv no yog siv rau hauv vitro qualitative detection ntawm Mycobacterium tuberculosis DNA nyob rau hauv tib neeg hnoos qeev, khoom kab lis kev cai (LJ Medium) thiab kua kab lis kev cai (MGIT Medium), bronchial lavage kua, thiab cov kev hloov nyob rau hauv lub 507-533 amino acid codon cheeb tsam (81bp, rifampicin resistance lub cheeb tsam ntawm mycobacteria) rifampicin tsis kam, nrog rau kev hloov pauv hauv qhov chaw hloov pauv tseem ceeb ntawm Mycobacterium tuberculosis isoniazid resistance.Nws muab kev pabcuam rau kev kuaj mob ntawm tus kab mob Mycobacterium tuberculosis, thiab nws kuaj pom cov noob tseem ceeb ntawm rifampicin thiab isoniazid, uas pab kom nkag siab txog cov tshuaj tiv thaiv ntawm Mycobacterium tuberculosis.
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Mycobacterium Tuberculosis INH Mutation
Cov khoom siv no tsim nyog rau kev txheeb xyuas qhov zoo ntawm qhov chaw hloov pauv tseem ceeb hauv tib neeg cov hnoos qeev cov qauv sau los ntawm Tubercle bacillus zoo cov neeg mob uas ua rau mycobacterium tuberculosis INH: InhA txhawb nqa cheeb tsam -15C>T, -8T>A, -8T>C; AhpC txhawb nqa cheeb tsam -12C>T, -6G>A; Homozygous mutation ntawm KatG 315 codon 315G> A, 315G> C .
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Mycobacterium Tuberculosis Rifampicin Resistance
Cov khoom siv no tsim nyog rau kev kuaj pom zoo ntawm homozygous kev hloov pauv hauv 507-533 amino acid codon cheeb tsam ntawm rpoB noob uas ua rau Mycobacterium tuberculosis rifampicin tsis kam.
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Mycobacterium Tuberculosis Nucleic Acid thiab Rifampicin Resistance
Cov khoom siv no tsim nyog rau kev kuaj pom zoo ntawm Mycobacterium tuberculosis DNA hauv tib neeg cov hnoos qeev hauv vitro, nrog rau kev hloov pauv homozygous hauv 507-533 amino acid codon cheeb tsam ntawm rpoB noob uas ua rau Mycobacterium tuberculosis rifampicin tsis kam.
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Mycobacterium Tuberculosis DNA
Nws yog qhov tsim nyog rau kev kuaj pom zoo ntawm Mycobacterium tuberculosis DNA hauv tib neeg cov tshuaj hnoos qeev, thiab tsim nyog rau kev kuaj mob ntawm tus kab mob Mycobacterium tuberculosis.
