● Mycobacterium Tuberculosis
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Mycobacterium Tuberculosis Nucleic Acid thiab Rifampicin (RIF), Isoniazid Resistance (INH)
Cov khoom no tsim nyog rau kev kuaj pom zoo ntawm Mycobacterium tuberculosis DNA hauv tib neeg cov hnoos qeev hauv vitro, nrog rau kev hloov pauv homozygous hauv thaj tsam 507-533 amino acid codon (81bp, rifampicin kuj txiav txim siab cheeb tsam) ntawm rpoB noob uas ua rau Mycobacterium tuberculosis. rifampicin tsis kam.
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Mycobacterium Tuberculosis Isoniazid Resistance Mutation
Cov khoom siv no tsim nyog rau kev tshawb nrhiav qhov zoo ntawm qhov chaw hloov pauv tseem ceeb hauv tib neeg cov hnoos qeev cov qauv sau los ntawm Tubercle bacillus zoo cov neeg mob uas ua rau mycobacterium tuberculosis isoniazid tsis kam: InhA txhawb cheeb tsam -15C>T, -8T>A, -8T>C;AhpC txhawb nqa cheeb tsam -12C>T, -6G>A;Homozygous mutation ntawm KatG 315 codon 315G> A, 315G> C .
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Mycobacterium Tuberculosis Rifampicin Resistance
Cov khoom siv no tsim nyog rau kev kuaj pom zoo ntawm homozygous kev hloov pauv hauv 507-533 amino acid codon cheeb tsam ntawm rpoB noob uas ua rau Mycobacterium tuberculosis rifampicin tsis kam.
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Mycobacterium Tuberculosis Nucleic Acid thiab Rifampicin Resistance
Cov khoom siv no tsim nyog rau kev kuaj pom zoo ntawm Mycobacterium tuberculosis DNA hauv tib neeg cov hnoos qeev hauv vitro, nrog rau kev hloov pauv homozygous hauv thaj tsam 507-533 amino acid codon ntawm rpoB noob uas ua rau Mycobacterium tuberculosis rifampicin tsis kam.
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Mycobacterium Tuberculosis INH Resistance
Cov khoom siv no yog siv los txheeb xyuas cov noob hloov pauv ntawm 315th amino acid ntawm katG gene (K315G>C) thiab cov noob hloov pauv ntawm thaj chaw txhawb nqa ntawm InhA gene (- 15 C> T).
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Mycobacterium Tuberculosis DNA
Nws yog qhov tsim nyog rau kev kuaj pom zoo ntawm Mycobacterium tuberculosis DNA hauv tib neeg cov tshuaj hnoos qeev, thiab tsim nyog rau kev kuaj mob ntawm tus kab mob Mycobacterium tuberculosis.
