Mycobacterium tuberculosis nucleic acid thiab rifampicin (RIF), Kuj (Inflers)

Mycobacacterium tuberculosis nucleic acid thiab rifampicin (RIF), Kuj (INVE) Featured Duab

Cov lus piav qhia luv luv:

Cov khoom siv no yog siv rau hauv cov vitro tsim nyog nrhiav tau ntawm mycobacterium tuberculosis DNA hauv tib neeg cov kab lis kev cai (LJ , Rifampicin resistance txiav txim siab thaj av) ntawm Rpob Gene ntawm MyCobacterium tuberculosis Rifampicin tsis kam, nrog rau kev hloov pauv hauv MyCobacterium tuberculosis is.oniazid, uas pab kom nkag siab txog cov tshuaj tiv thaiv MyCobacterium tuberculosis kis los ntawm tus neeg mob.

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HWTS-RT147 MyCobacterium tuberculosis nucleic acid thiab rifampicin (RIF), (IN) Cov Khoom Siv Mus Nrhiav)

Kev kawm

Mycobacacterium tuberculosis, tsis ntev li cov tubercle Bacillus (TB)^[1]Cov. Txawm li cas los xij, vim kev siv tshuaj tsis raug ntawm cov tshuaj tiv thaiv kab mob ntawm mycobacterium tuberculosis, myCobacterium tuberculosis, thiab cov ntawv phom tshwj xeeb yog multidrug-resistant tuberculosis (mdr- TB), uas yog tiv rau ob qho tshuaj uas feem ntau thiab siv tau zoo, Rifampicin thiab isoniazid^[2].

Qhov teeb meem ntawm cov yeeb yaj kiab ntawm cov tuberculosis dej tsis kam muaj nyob rau hauv txhua lub teb chaws tshawb fawb los ntawm tus uas. Txhawm rau muab cov phiaj xwm kho mob ntau dua rau cov neeg mob ntsws, nws yog qhov tsim nyog los tshawb xyuas cov neeg mob ntsws, uas tau dhau los ua tus neeg kuaj mob^[3]Cov. Txawm hais tias qhov kev tshawb pom ntawm Rifampicin tsis muaj yuav luag sib npaug ntawm MDR-TODBicin tsis quav ntsej txog cov neeg mob mono-resistant rifampicin (rhiab heev rau isoniazid tab sis tsis kam Rifampicin), uas tej zaum yuav ua rau cov neeg mob raug tsim nyog ntawm kev kho kom tsis muaj peev xwm. Yog li ntawd, isoniazid thiab Rifampicin Tsis kam ua cov txuj ci yog yam tsawg kawg nkaus uas yuav tsum tau tsim nyog rau txhua hom kev tswj Dr-TB^[⁴^].

Kev tsis muaj

Chaw ntim khoom	≤-18 ℃
Txee-Lub Neej	12 lub hlis
Zauv Hom	Kev hnoos qeev, cov kab lis kev cai (LJ nruab nrab), cov kab lis kev cai ua kua (mgit nruab nrab)
CV	<0%
Lub lab	Lub lod ntawm cov khoom siv rau ntes mycobacterium tuberculosis yog 10 tus kab mob / mL;Lub lod ntawm cov khoom siv rau kev kuaj pom Rifampicin tsiaj qus thiab Mutant hom yog 150 tus kab mob / mL; Lub lod ntawm cov khoom siv rau kev kuaj tau yog cov tsiaj qus thiab hom mutant yog 200 txiv kab ntxwv / ml.
Yam tshwj xeeb	1) Tsis muaj ib qho kev tawm tsam hla thaum siv cov khoom siv los tshawb xyuas tib neeg cov pa gacogens, thiab 29 hom tuberculous myCobacteria (raws li qhia hauv Table 3).2) Tsis muaj ib qho kev tawm tsam hla thaum siv cov khoom siv sib tsoo ntawm kev hloov pauv ntawm cov Rifampicin thiab Isoniazid rhiab mycobacterium tuberculosis (raws li qhia hauv rooj 4).3) Cov tshuaj cuam tshuam rau hauv cov qauv yuav tsum tau kuaj, xws li Rifamputol (ethancutol (11mg / l), oxymetazoline (1mg / l), mupirocin (20mg / l), pyrazinamide (45mg / l), zanamivir (0.5mg / l), dexamethasone (20mg / l) tshuaj, tsis muaj qhov cuam tshuam rau cov khoom kuaj cov khoom siv.
Muaj cov cuab yeej siv tau	Slan-96p RO-LUB SIJHAWM PRR TSHUAB (Hongshi Medical Technology Co., Ltd.), Biorad Cfx96 REO-SIJHAWM PCR system