15-hom HR-HPV MRNA nrhiav kom pom tias muaj thiab kev ua haujlwm ntawm HR-HPV

Cais mob cancer, qhov ua rau kev tuag ntawm lub nroog menyuam yaus thoob ntiaj teb, feem ntau yog tshwm sim los ntawm tus mob HPV. Lub oncogenic muaj peev xwm ntawm HR-HPV kis mob yog nyob ntawm cov kev qhia nce ntxiv ntawm E6 thiab E7 noob. E6 thiab E7 proteins khi rau cov qog nqaij cov protein p53 thiab muaj feem, thiab tsav lub tsev pheeb suab cell proliferation thiab kev hloov pauv.

Txawm li cas los xij, HPV DNA kuaj lees paub meej, nws tsis paub ntawm cov latent thiab nquag hloov cov kab mob. Nyob rau hauv sib piv, kev kuaj pom ntawm HPV E6 / E7 MRMA cov ntawv tshaj tawm ua haujlwm ntawm lub ncauj tsev menyuam yaus uas muaj peev xwm tshaj tawm, thiab yog li, yog qhov muaj txiaj ntsig zoo tshaj plaws ntawm cov menyuam yaus

HPV E6 / E7 MRNAKev kuaj mob muaj cov txiaj ntsig tseem ceeb hauv cov tsev pheeb suab cancer tiv thaiv kab mob cancer:

• Kev soj ntsuam muaj feem muaj kev pheej hmoo: Cov kab mob HPV, muab cov kev ntsuas kev pheej hmoo pheej hmoo ntau dua HPV DNA kuaj.
• Kev ua yeeb yam zoo: Cov kws kho mob cov kws kho mob hauv kev txheeb xyuas cov neeg mob uas xav tau kev tshawb xyuas ntxiv,
• Cov cuab yeej kuaj xyuas cov cuab yeej: Tej zaum yuav ua qhov cuab yeej sib tw pom yav tom ntej, tshwj xeeb tshaj yog rau cov neeg pheej hmoo siab.
• 15 hom kev pheej hmoo siab ntawm tib neeg mcrillomavirus E6 / E7 GRE pom cov khoom siv HRV uas muaj peev xwm nrhiav tau HPV tshuaj ntsuam thiab / lossis tswj hwm tus neeg mob.

Khoom nta:

• Pab them tag nrho: 15 HR-HPV cov kab mob cuam tshuam nrog cov menyuam kab mob cancer uas them rau;
• Zoo heev rhiab: 500 Luam / ML;
• Superior tshwj xeeb: Tsis muaj cov khaub lig ua nrog cytomegalovirus, HSV II thiab tib neeg cov DNA zoo nkauj;
• Raug nqi-ua tau zoo: Kev kuaj cov hom phiaj ntau sib txuam nrog cov kab mob ua tau, kom txo qis kev ntsuam xyuas nrog cov nqi ntxiv;
• Cov txheej txheem zoo heev: IC rau tag nrho cov txheej txheem;
• Kev sib piv: nrog cov tshuab loj tshaj plaws;