Kev Tshawb Pom 15-Hom HR-HPV mRNA - Txheeb Xyuas Qhov Muaj thiab Kev Ua Haujlwm ntawm HR-HPV

Mob qog nqaij hlav hauv tsev menyuam, qhov ua rau cov poj niam tuag coob tshaj plaws thoob ntiaj teb, feem ntau yog los ntawm kev kis tus kab mob HPV. Lub peev xwm oncogenic ntawm kev kis tus kab mob HR-HPV nyob ntawm qhov kev qhia tawm ntawm cov noob E6 thiab E7. Cov protein E6 thiab E7 khi rau cov protein tiv thaiv qog nqaij hlav p53 thiab pRb, thiab tsav cov hlwb hauv tsev menyuam kom loj hlob thiab hloov pauv.

Txawm li cas los xij, kev kuaj HPV DNA lees paub tias muaj tus kab mob, nws tsis paub qhov txawv ntawm cov kab mob latent thiab cov kab mob uas tseem tab tom kis. Qhov sib txawv, kev kuaj pom HPV E6/E7 mRNA transcripts ua haujlwm ua tus cim qhia tshwj xeeb dua ntawm kev qhia tawm ntawm cov kab mob oncogene uas tseem tab tom kis, thiab yog li, yog qhov tseeb dua los kwv yees qhov tseeb ntawm cov qog nqaij hlav hauv lub caj dab (CIN) lossis cov qog nqaij hlav uas nkag mus rau hauv lub cev.

HPV E6/E7 mRNAkev kuaj mob muaj cov txiaj ntsig zoo hauv kev tiv thaiv mob qog nqaij hlav hauv tsev menyuam:

• Kev Ntsuam Xyuas Kev Pheej Hmoo Kom Tseeb: Txheeb xyuas cov kab mob HPV uas tseem muaj, muaj kev pheej hmoo siab, muab kev ntsuam xyuas kev pheej hmoo kom meej dua li kev kuaj HPV DNA.
• Kev Xaiv Tshuaj Zoo: Qhia cov kws kho mob kom paub cov neeg mob uas xav tau kev tshawb nrhiav ntxiv, txo cov txheej txheem tsis tsim nyog.
• Cov Cuab Yeej Siv Tau Los Tshuaj Xyuas: Tej zaum yuav siv tau ua ib qho cuab yeej tshuaj xyuas ib leeg yav tom ntej, tshwj xeeb tshaj yog rau cov pej xeem uas muaj kev pheej hmoo siab.
• 15 Hom Kab Mob Papillomavirus E6/E7 Gene mRNA Detection Kit (Fluorescence PCR) uas muaj feem yuav kis tau kab mob HR-HPV, yog ib qho cuab yeej pab tau rau kev kuaj mob HPV thiab/lossis kev tswj hwm tus neeg mob.

Cov yam ntxwv ntawm cov khoom:

• Kev them tag nrho: 15 hom kab mob HR-HPV uas cuam tshuam nrog mob qog nqaij hlav hauv tsev menyuam;
• Kev rhiab heev zoo heev: 500 daim / mL;
• Kev tshwj xeeb zoo tshaj plawsTsis muaj kev sib txuas nrog cytomegalovirus, HSV II thiab tib neeg genomic DNA;
• Tus nqi tsim nyog: Cov hom phiaj kuaj mob muaj feem cuam tshuam nrog cov kab mob uas yuav tshwm sim, kom txo qis kev kuaj mob tsis tsim nyog nrog cov nqi ntxiv;
• Qhov tseeb zoo heev: IC rau tag nrho cov txheej txheem;
• Kev sib raug zoo dav dav: Nrog cov kab ke PCR tseem ceeb;