Qhov tseem ceeb BCR-ABL Detection rau CML kev kho mob

Chronic myelogenousleukemia (CML) yog ib hom kab mob qog nqaij hlav ntawm hematopoietic qia hlwb. Ntau tshaj 95% ntawm CML cov neeg mob nqa Philadelphia chromosome (Ph) hauv lawv cov qe ntshav. Thiab BCR-ABL fusion noob yog tsim los ntawm kev hloov pauv ntawm ABL proto-oncogene (Abelson murine leukemia viral oncogene homolog 1) ntawm caj npab ntev ntawm chromosome 9 (9q34) thiab thaj tsam breakpoint pawg (BCR) noob ntawm caj npab ntev ntawm chromosome 22 (22q11). Nws cov fusion protein encoded los ntawm cov noob no muaj tyrosine kinase (TK) kev ua, thiab ua kom nws txoj hauv kev qis qis (xws li RAS, PI3K, thiab JAK / STAT) los txhawb kev faib cell thiab inhibit cell apoptosis, ua rau cov hlwb proliferate malignantly, thiab yog li ua rau tshwm sim ntawm CML.

BCR-ABL fusion noob, uas yog ib qho tseem ceeb hauv kev txhim kho CML, ua tus cim tseem ceeb ntawm kev kuaj mob. ntawm CML. Nws qhov kev tshawb nrhiav pab saib xyuas tus neeg mob's teb rau tyrosine kinase inhibitors (TKIs) thiab kwv yees leukemia rov tshwm sim, uas yog qhov tseem ceeb rau kev tswj hwm tus neeg mob zoo CML.

Human BCR-ABLFusion Gene Mutation Detection Kitlos ntawm Macro & Micro-Test rau kev kuaj pom zoo ntawm BCR-ABL hauv CML cov neeg mob, pab CML kev kuaj mob thiab taw qhia cov kev kho mob tshwj xeeb txhawm rau txhim kho cov tswv yim kho mob rau kev tswj tus neeg mob zoo.BCR-ABL fusion gene, qhoyogtseem ceebhauv kev loj hlob ntawm CML,ua hauj lwm raws li ib tug tseem ceeb diagnostic markerofCML. Nws nrhiav tau pabsaib xyuastus neeg mob'sTeb rau tyrosine kinase inhibitors (TKIs)thiabkwv yees leukemia rov tshwm sim, yogqhov tseem ceebto siv tauCMLkev tswj tus neeg mob.

Tib neeg BCR-ABL Fusion Gene Mutation Detection Kit los ntawm Macro & Micro-Test rau kev kuaj pom zoo ntawm BCR-ABL hauv CML cov neeg mob, pabCMLkuaj mobthiabcov lus qhiatsom rau kev kho mobtooptimiz uaeCov tswv yim kho mob rau kev tswj tus neeg mob zoo.

Kev davDkev xaiv:Ib txhijkuaj pomrau3Hom fusion noob (P210, P190, P230)raubroad kev pab them nqi thiabtiv thaiv los ntawm cov teeb meem tsis tau;

High Sensitivity:Cov kua version kuaj pom fusion noobnrog LoD1000 daim / ml,thiab lub lyophilized versionof 500 daim / ml;

Zoo heevAqhov tseeb: Isab hauvtswjthiab UNG enzyme los tiv thaiv qhov tsis zoo&yam tsis zoo;

Kev ua haujlwm yooj yim thiab ua haujlwm tau zoo:Kaw-tube ua haujlwm,dawb ntawm cov khoomtom qab ua tiav,thiabkuaj pomhauv60 feebrauLub hom phiaj thiab txhim khu kev qha cov txiaj ntsig;

NtauKev xaiv:Kua thiab lyophilized versions rau cov neeg siv khoom xaiv;

Wide Compatibility:Tau tshaj PCR feem ntau rau kev siv dav hauv lab.